Gene description for Acot7
Gene name acyl-CoA thioesterase 7
Gene symbol Acot7
Other names/aliases 2410041A17Rik
Ach1
Act
Bach
CTE-IIa
Cte-II
Lach1
Species Mus musculus
 Database cross references - Acot7
ExoCarta ExoCarta_70025
Entrez Gene 70025
UniProt Q91V12  
 Acot7 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Acot7
Molecular Function
    fatty-acyl-CoA binding GO:0000062 ISO
    carboxylic ester hydrolase activity GO:0052689 IEA
    protein homodimerization activity GO:0042803 ISO
    hydrolase activity GO:0016787 IEA
    long-chain fatty acyl-CoA binding GO:0036042 ISO
    palmitoyl-CoA hydrolase activity GO:0016290 ISO
    acyl-CoA hydrolase activity GO:0047617 ISO
Biological Process
    medium-chain fatty acid biosynthetic process GO:0051792 ISO
    palmitic acid biosynthetic process GO:1900535 ISO
    metabolic process GO:0008152 ISO
    fatty acid catabolic process GO:0009062 IDA
    medium-chain fatty-acyl-CoA catabolic process GO:0036114 ISO
    long-chain fatty-acyl-CoA catabolic process GO:0036116 ISO
    coenzyme A biosynthetic process GO:0015937 ISO
Subcellular Localization
    nucleoplasm GO:0005654 ISO
    cytosol GO:0005829 ISO
    cell body GO:0044297 IDA
    cytoplasm GO:0005737 ISO
    neuron projection GO:0043005 IDA
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Acot7 in exosomes
1
Experiment ID 210
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD81|FLOT1
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Acot7
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Acot7 is involved
No pathways found





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