Gene description for Cd248
Gene name CD248 antigen, endosialin
Gene symbol Cd248
Other names/aliases 2610111G01Rik
AI842296
Cd164l1
Tem1
Species Mus musculus
 Database cross references - Cd248
ExoCarta ExoCarta_70445
Vesiclepedia VP_70445
Entrez Gene 70445
UniProt Q91V98  
 Cd248 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Cd248
Molecular Function
    calcium ion binding GO:0005509 IEA
    carbohydrate binding GO:0030246 IEA
    extracellular matrix binding GO:0050840 IBA
    extracellular matrix binding GO:0050840 IDA
    extracellular matrix protein binding GO:1990430 IBA
Biological Process
    fibroblast migration GO:0010761 IMP
    cell migration GO:0016477 IBA
    fibroblast proliferation GO:0048144 IMP
    positive regulation of fibroblast proliferation GO:0048146 IMP
    lymph node development GO:0048535 IMP
    anatomical structure regression GO:0060033 IMP
    endothelial cell apoptotic process GO:0072577 IMP
    positive regulation of endothelial cell apoptotic process GO:2000353 IMP
Subcellular Localization
    cytoplasm GO:0005737 IDA
    plasma membrane GO:0005886 ISO
    external side of plasma membrane GO:0009897 IBA
 Experiment description of studies that identified Cd248 in exosomes
1
Experiment ID 210
MISEV standards
EM
Biophysical techniques
CD81|FLOT1
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Cd248
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Cfd  
Affinity Capture-MS Mus musculus
2 Fndc5  
Affinity Capture-MS Mus musculus
3 Tfap2c  
Co-fractionation Mus musculus
4 Lgals3bp 19039
Co-fractionation Mus musculus
View the network image/svg+xml
 Pathways in which Cd248 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here