Gene description for Cd248
Gene name CD248 antigen, endosialin
Gene symbol Cd248
Other names/aliases 2610111G01Rik
AI842296
Cd164l1
Tem1
Species Mus musculus
 Database cross references - Cd248
ExoCarta ExoCarta_70445
Entrez Gene 70445
UniProt Q91V98  
 Cd248 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Cd248
Molecular Function
    calcium ion binding GO:0005509 IEA
    carbohydrate binding GO:0030246 IEA
    extracellular matrix binding GO:0050840 IDA
Biological Process
    lymph node development GO:0048535 IMP
    positive regulation of endothelial cell apoptotic process GO:2000353 IMP
    positive regulation of cell proliferation GO:0008284 IMP
    cell migration GO:0016477 IMP
    anatomical structure regression GO:0060033 IMP
Subcellular Localization
    integral component of membrane GO:0016021 IEA
    plasma membrane GO:0005886 ISO
    cytoplasm GO:0005737 IDA
    membrane GO:0016020 IEA
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Cd248 in exosomes
1
Experiment ID 210
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD81|FLOT1
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Cd248
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Cd248 is involved
No pathways found





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