Gene description for Prdm16
Gene name	PR domain containing 16
Gene symbol	Prdm16
Other names/aliases	5730557K01Rik csp1 mel1
Species	Mus musculus
Database cross references - Prdm16
ExoCarta	ExoCarta_70673
Vesiclepedia	VP_70673
Entrez Gene	70673
UniProt	A2A935
Prdm16 identified in sEVs derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Prdm16

Molecular Function     transcription cis-regulatory region binding GO:0000976 ISO     RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IBA     DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227 ISO     DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 IBA     DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 IDA     transcription coregulator activity GO:0003712 IBA     transcription coactivator activity GO:0003713 IDA     protein binding GO:0005515 IPI     sequence-specific DNA binding GO:0043565 IDA     sequence-specific DNA binding GO:0043565 ISO     SMAD binding GO:0046332 IPI     metal ion binding GO:0046872 IEA     histone H3K9 methyltransferase activity GO:0046974 IDA     DNA-binding transcription factor binding GO:0140297 ISO     histone H3K9me2 methyltransferase activity GO:0140947 IEA     histone H3K9 monomethyltransferase activity GO:0140948 IEA Biological Process     negative regulation of transcription by RNA polymerase II GO:0000122 IMP     negative regulation of transcription by RNA polymerase II GO:0000122 ISO     negative regulation of transcription by RNA polymerase II GO:0000122 ISS     chromatin remodeling GO:0006338 IEA     regulation of transcription by RNA polymerase II GO:0006357 IBA     stem cell population maintenance GO:0019827 IGI     stem cell population maintenance GO:0019827 IMP     neurogenesis GO:0022008 IDA     negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 IMP     negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 ISO     negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 ISS     negative regulation of granulocyte differentiation GO:0030853 ISO     negative regulation of granulocyte differentiation GO:0030853 ISS     methylation GO:0032259 IEA     somatic stem cell population maintenance GO:0035019 IDA     regulation of cellular respiration GO:0043457 IDA     tongue development GO:0043586 IMP     negative regulation of DNA-templated transcription GO:0045892 IDA     negative regulation of DNA-templated transcription GO:0045892 ISO     negative regulation of DNA-templated transcription GO:0045892 ISS     positive regulation of DNA-templated transcription GO:0045893 IDA     positive regulation of DNA-templated transcription GO:0045893 IDA     positive regulation of DNA-templated transcription GO:0045893 ISO     positive regulation of DNA-templated transcription GO:0045893 ISS     positive regulation of transcription by RNA polymerase II GO:0045944 IEA     white fat cell differentiation GO:0050872 IDA     brown fat cell differentiation GO:0050873 IDA     brown fat cell differentiation GO:0050873 IMP     brown fat cell differentiation GO:0050873 IMP     roof of mouth development GO:0060021 IMP     heterochromatin organization GO:0070828 IMP     positive regulation of brown fat cell differentiation GO:0090336 IMP     positive regulation of cold-induced thermogenesis GO:0120162 IMP Subcellular Localization     nucleus GO:0005634 IBA     nucleus GO:0005634 IDA     nucleus GO:0005634 ISO     nucleoplasm GO:0005654 ISO     nucleoplasm GO:0005654 TAS     transcription regulator complex GO:0005667 IC     cytoplasm GO:0005737 IEA     cytosol GO:0005829 ISO     aggresome GO:0016235 ISO     transcription repressor complex GO:0017053 IDA