Gene description for Pgm2l1
Gene name phosphoglucomutase 2-like 1
Gene symbol Pgm2l1
Other names/aliases 4931406N15Rik
AI553438
BM32A
Species Mus musculus
 Database cross references - Pgm2l1
ExoCarta ExoCarta_70974
Vesiclepedia VP_70974
Entrez Gene 70974
UniProt Q8CAA7  
 Pgm2l1 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Pgm2l1
Molecular Function
    intramolecular phosphotransferase activity GO:0016868 IEA
    metal ion binding GO:0046872 IEA
    glucose-1,6-bisphosphate synthase activity GO:0047933 IBA
    glucose-1,6-bisphosphate synthase activity GO:0047933 ISO
    glucose-1,6-bisphosphate synthase activity GO:0047933 ISS
Biological Process
    glucose metabolic process GO:0006006 IEA
Subcellular Localization
    cytosol GO:0005829 IEA
 Experiment description of studies that identified Pgm2l1 in sEVs
1
Experiment ID 15
MISEV standards
✔
EM
Biophysical techniques
✔
CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Pgm2l1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Pgm2l1 is involved
PathwayEvidenceSource
Glucose metabolism IEA Reactome
Glycolysis IEA Reactome
Metabolism IEA Reactome
Metabolism of carbohydrates IEA Reactome





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