Gene description for Naa40
Gene name N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
Gene symbol Naa40
Other names/aliases 4931433E08Rik
AU023197
Nat11
Species Mus musculus
 Database cross references - Naa40
ExoCarta ExoCarta_70999
Vesiclepedia VP_70999
Entrez Gene 70999
UniProt Q8VE10  
 Naa40 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Naa40
Molecular Function
    histone H4 acetyltransferase activity GO:0010485 IBA
    histone H4 acetyltransferase activity GO:0010485 ISO
    histone H4 acetyltransferase activity GO:0010485 ISS
    histone H2A acetyltransferase activity GO:0043998 IBA
    histone H2A acetyltransferase activity GO:0043998 ISO
    histone H2A acetyltransferase activity GO:0043998 ISS
    peptide-serine-alpha-N-acetyltransferase activity GO:1990189 IBA
    peptide-serine-alpha-N-acetyltransferase activity GO:1990189 ISO
    peptide-serine-alpha-N-acetyltransferase activity GO:1990189 ISS
Biological Process
    chromatin remodeling GO:0006338 IEA
    lipid metabolic process GO:0006629 IMP
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleoplasm GO:0005654 IEA
    nucleoplasm GO:0005654 ISO
    cytosol GO:0005829 IEA
    cytosol GO:0005829 ISO
    centriolar satellite GO:0034451 IEA
    centriolar satellite GO:0034451 ISO
 Experiment description of studies that identified Naa40 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Naa40
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Eed  
Affinity Capture-MS Mus musculus
View the network image/svg+xml
 Pathways in which Naa40 is involved
No pathways found





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