Gene description for Naa40
Gene name N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
Gene symbol Naa40
Other names/aliases 4931433E08Rik
AU023197
Nat11
Species Mus musculus
 Database cross references - Naa40
ExoCarta ExoCarta_70999
Entrez Gene 70999
UniProt Q8VE10  
 Naa40 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Naa40
Molecular Function
    UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity GO:0043764 IEA
    succinyltransferase activity GO:0016748 IEA
    acetyl-CoA:L-lysine N6-acetyltransferase GO:0090595 IEA
    octanoyltransferase activity GO:0016415 IEA
    C-palmitoyltransferase activity GO:0016454 IEA
    C-acyltransferase activity GO:0016408 IEA
    ergosterol O-acyltransferase activity GO:0034737 IEA
    molecular_function GO:0003674 ND
    2-methylhexanoyl-CoA C-acetyltransferase activity GO:0034915 IEA
    transferase activity, transferring acyl groups GO:0016746 IEA
    sinapoyltransferase activity GO:0016752 IEA
    N-succinyltransferase activity GO:0016749 IEA
    N-palmitoyltransferase activity GO:0019105 IEA
    serine O-acyltransferase activity GO:0016412 IEA
    acylglycerol O-acyltransferase activity GO:0016411 IEA
    sterol O-acyltransferase activity GO:0004772 IEA
    S-acyltransferase activity GO:0016417 IEA
    dihydrolipoamide branched chain acyltransferase activity GO:0004147 IEA
    S-succinyltransferase activity GO:0016751 IEA
    palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity GO:0008951 IEA
    malonyltransferase activity GO:0016420 IEA
    lanosterol O-acyltransferase activity GO:0034738 IEA
    peptidyl-lysine N6-myristoyltransferase activity GO:0018030 IEA
    S-malonyltransferase activity GO:0016419 IEA
    azetidine-2-carboxylic acid acetyltransferase activity GO:0046941 IEA
    O-acetyltransferase activity GO:0016413 IEA
    2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity GO:0034851 IEA
    O-sinapoyltransferase activity GO:0016753 IEA
    carnitine O-acyltransferase activity GO:0016406 IEA
    protein-cysteine S-myristoyltransferase activity GO:0019705 IEA
    Ras palmitoyltransferase activity GO:0043849 IEA
    benzoyl acetate-CoA thiolase activity GO:0018711 IEA
    naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity GO:0034848 IEA
    palmitoyltransferase activity GO:0016409 IEA
    myristoyltransferase activity GO:0019107 IEA
    O-octanoyltransferase activity GO:0016414 IEA
    S-acetyltransferase activity GO:0016418 IEA
    keto acid formate lyase activity GO:0043806 IEA
    3-ketopimelyl-CoA thiolase activity GO:0018713 IEA
    butyryl-CoA 2-C-propionyltransferase activity GO:0034919 IEA
    2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity GO:0034945 IEA
    peptidyl-lysine N6-palmitoyltransferase activity GO:0018031 IEA
    acyl-CoA N-acyltransferase activity GO:0019186 IEA
    protein-cysteine S-acyltransferase activity GO:0019707 IEA
    O-acyltransferase activity GO:0008374 IEA
    transferase activity GO:0016740 IEA
    L-2-aminoadipate N-acetyltransferase activity GO:0043741 IEA
    glucosaminyl-phosphotidylinositol O-acyltransferase activity GO:0032216 IEA
    O-palmitoyltransferase activity GO:0016416 IEA
    acetyltransferase activity GO:0016407 IEA
    N-acyltransferase activity GO:0016410 IEA
    3-hydroxybutyryl-CoA thiolase activity GO:0018712 IEA
    N-acetyltransferase activity GO:0008080 IEA
    O-succinyltransferase activity GO:0016750 IEA
    dihydrolipoamide S-acyltransferase activity GO:0030523 IEA
    peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor GO:0052858 IEA
Biological Process
    lipid metabolic process GO:0006629 IMP
Subcellular Localization
    cellular_component GO:0005575 ND
 Experiment description of studies that identified Naa40 in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Naa40
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Naa40 is involved
No pathways found





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