Gene description for Ccdc57
Gene name coiled-coil domain containing 57
Gene symbol Ccdc57
Other names/aliases 4933434G05Rik
Species Mus musculus
 Database cross references - Ccdc57
ExoCarta ExoCarta_71276
Vesiclepedia VP_71276
Entrez Gene 71276
UniProt Q6PHN1  
 Ccdc57 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Ccdc57
Molecular Function
    molecular_function GO:0003674 ND
Biological Process
    G2/M transition of mitotic cell cycle GO:0000086 ISO
    G2/M transition of mitotic cell cycle GO:0000086 ISS
    microtubule nucleation GO:0007020 IBA
    microtubule nucleation GO:0007020 ISO
    microtubule nucleation GO:0007020 ISS
    centriole replication GO:0007099 IBA
    centriole replication GO:0007099 ISO
    centriole replication GO:0007099 ISS
    positive regulation of mitotic cell cycle GO:0045931 IBA
    positive regulation of mitotic cell cycle GO:0045931 ISO
    positive regulation of mitotic cell cycle GO:0045931 ISS
    cilium assembly GO:0060271 IBA
    cilium assembly GO:0060271 IMP
    cilium assembly GO:0060271 ISO
Subcellular Localization
    cytoplasm GO:0005737 IEA
    centrosome GO:0005813 ISO
    centrosome GO:0005813 ISS
    centriole GO:0005814 IBA
    centriole GO:0005814 ISO
    centriole GO:0005814 ISS
    spindle microtubule GO:0005876 IBA
    spindle microtubule GO:0005876 ISO
    spindle microtubule GO:0005876 ISS
    centriolar satellite GO:0034451 IBA
    centriolar satellite GO:0034451 ISO
    centriolar satellite GO:0034451 ISS
 Experiment description of studies that identified Ccdc57 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Ccdc57
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ccdc57 is involved
No pathways found





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