Gene description for Slc29a3
Gene name solute carrier family 29 (nucleoside transporters), member 3
Gene symbol Slc29a3
Other names/aliases 4933435C21Rik
AW987637
Ent3
Species Mus musculus
 Database cross references - Slc29a3
ExoCarta ExoCarta_71279
Entrez Gene 71279
UniProt Q99P65  
 Slc29a3 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Slc29a3
Molecular Function
    nucleoside transmembrane transporter activity GO:0005337 ISO
Biological Process
    nucleoside transport GO:0015858 ISO
    nucleoside transmembrane transport GO:1901642 ISO
    transport GO:0006810 IEA
Subcellular Localization
    endosome GO:0005768 IEA
    membrane GO:0016020 IEA
    lysosomal membrane GO:0005765 ISO
    lysosome GO:0005764 IEA
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified Slc29a3 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Slc29a3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Slc29a3 is involved
PathwayEvidenceSource
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane IEA Reactome





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