Gene description for Slc29a3
Gene name solute carrier family 29 (nucleoside transporters), member 3
Gene symbol Slc29a3
Other names/aliases 4933435C21Rik
AW987637
Ent3
Species Mus musculus
 Database cross references - Slc29a3
ExoCarta ExoCarta_71279
Vesiclepedia VP_71279
Entrez Gene 71279
UniProt Q99P65  
 Slc29a3 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Slc29a3
Molecular Function
    neurotransmitter transmembrane transporter activity GO:0005326 ISO
    neurotransmitter transmembrane transporter activity GO:0005326 ISS
    nucleoside transmembrane transporter activity GO:0005337 IBA
    nucleoside transmembrane transporter activity GO:0005337 IMP
    nucleoside transmembrane transporter activity GO:0005337 ISO
    nucleoside transmembrane transporter activity GO:0005337 ISS
    monoamine transmembrane transporter activity GO:0008504 ISO
    monoamine transmembrane transporter activity GO:0008504 ISS
    organic cation transmembrane transporter activity GO:0015101 ISO
    organic cation transmembrane transporter activity GO:0015101 ISS
    nucleobase transmembrane transporter activity GO:0015205 ISO
    nucleobase transmembrane transporter activity GO:0015205 ISS
    guanine transmembrane transporter activity GO:0015208 ISO
    guanine transmembrane transporter activity GO:0015208 ISS
    uracil transmembrane transporter activity GO:0015210 ISO
    uracil transmembrane transporter activity GO:0015210 ISS
    cytidine transmembrane transporter activity GO:0015212 ISO
    cytidine transmembrane transporter activity GO:0015212 ISS
    uridine transmembrane transporter activity GO:0015213 ISO
    uridine transmembrane transporter activity GO:0015213 ISS
Biological Process
    neurotransmitter transport GO:0006836 IEA
    serotonin transport GO:0006837 ISO
    serotonin transport GO:0006837 ISS
    nucleobase transport GO:0015851 ISO
    nucleobase transport GO:0015851 ISS
    nucleoside transport GO:0015858 IMP
    nucleoside transport GO:0015858 ISO
    nucleoside transport GO:0015858 ISS
    cytidine transport GO:0015861 ISO
    cytidine transport GO:0015861 ISS
    uridine transmembrane transport GO:0015862 ISO
    uridine transmembrane transport GO:0015862 ISS
    dopamine transport GO:0015872 ISO
    dopamine transport GO:0015872 ISS
    norepinephrine transport GO:0015874 ISO
    norepinephrine transport GO:0015874 ISS
    adenosine transport GO:0032238 IMP
    adenosine transport GO:0032238 ISO
    adenosine transport GO:0032238 ISS
    inosine transport GO:0035340 ISO
    inosine transport GO:0035340 ISS
    nucleoside transmembrane transport GO:1901642 IMP
    nucleoside transmembrane transport GO:1901642 ISO
    nucleoside transmembrane transport GO:1901642 ISS
    guanine transmembrane transport GO:1903716 ISO
    guanine transmembrane transport GO:1903716 ISS
    uracil transmembrane transport GO:1903791 ISO
    uracil transmembrane transport GO:1903791 ISS
    pyrimidine nucleobase transmembrane transport GO:1904082 ISO
    pyrimidine nucleobase transmembrane transport GO:1904082 ISS
    purine nucleobase transmembrane transport GO:1904823 ISO
    purine nucleobase transmembrane transport GO:1904823 ISS
Subcellular Localization
    lysosomal membrane GO:0005765 ISO
    lysosomal membrane GO:0005765 ISS
    Golgi apparatus GO:0005794 IBA
    Golgi apparatus GO:0005794 IEA
    Golgi apparatus GO:0005794 ISO
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IEA
    late endosome membrane GO:0031902 ISO
    late endosome membrane GO:0031902 ISS
    mitochondrial membrane GO:0031966 IEA
    intracellular membrane-bounded organelle GO:0043231 ISO
 Experiment description of studies that identified Slc29a3 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Slc29a3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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