Gene description for Myo1e
Gene name myosin IE
Gene symbol Myo1e
Other names/aliases 2310020N23Rik
9130023P14Rik
AA407778
myosin-1e
myr 3
Species Mus musculus
 Database cross references - Myo1e
ExoCarta ExoCarta_71602
Vesiclepedia VP_71602
Entrez Gene 71602
UniProt E9Q634  
 Myo1e identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Myo1e
Molecular Function
    microfilament motor activity GO:0000146 IBA
    cytoskeletal motor activity GO:0003774 IEA
    calmodulin binding GO:0005516 ISO
    calmodulin binding GO:0005516 ISS
    ATP binding GO:0005524 IEA
    ATP hydrolysis activity GO:0016887 ISO
    ATP hydrolysis activity GO:0016887 ISS
    phosphatidylinositol binding GO:0035091 ISO
    phosphatidylinositol binding GO:0035091 ISS
    protein-containing complex binding GO:0044877 ISO
    actin filament binding GO:0051015 IBA
    actin filament binding GO:0051015 ISO
    actin filament binding GO:0051015 ISS
Biological Process
    vasculogenesis GO:0001570 IMP
    in utero embryonic development GO:0001701 IMP
    kidney development GO:0001822 IMP
    glomerular filtration GO:0003094 IMP
    endocytosis GO:0006897 IBA
    endocytosis GO:0006897 ISO
    endocytosis GO:0006897 ISS
    actin filament organization GO:0007015 IBA
    excretion GO:0007588 IMP
    hemopoiesis GO:0030097 IMP
    glomerulus development GO:0032835 IBA
    glomerular basement membrane development GO:0032836 IMP
    post-embryonic hemopoiesis GO:0035166 IMP
    platelet-derived growth factor receptor signaling pathway GO:0048008 IMP
    podocyte development GO:0072015 IMP
Subcellular Localization
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
    cytoskeleton GO:0005856 ISO
    cytoskeleton GO:0005856 ISS
    plasma membrane GO:0005886 IBA
    microvillus GO:0005902 IBA
    brush border GO:0005903 IDA
    adherens junction GO:0005912 IDA
    actin cytoskeleton GO:0015629 IBA
    myosin complex GO:0016459 IEA
    cuticular plate GO:0032437 IEA
    cuticular plate GO:0032437 ISO
    protein-containing complex GO:0032991 ISO
    clathrin-coated endocytic vesicle GO:0045334 ISO
    clathrin-coated endocytic vesicle GO:0045334 ISS
 Experiment description of studies that identified Myo1e in sEVs
1
Experiment ID 907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Myo1e
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Zbtb7b  
Affinity Capture-MS Mus musculus
2 Kctd13  
Affinity Capture-MS Mus musculus
3 Tmem173  
Proximity Label-MS Mus musculus
4 Eed  
Affinity Capture-MS Mus musculus
5 Afg3l2  
Co-fractionation Mus musculus
6 Nanog  
Affinity Capture-MS Mus musculus
7 Fancd2  
Affinity Capture-MS Mus musculus
View the network image/svg+xml
 Pathways in which Myo1e is involved
No pathways found





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