Gene description for Pitpnc1
Gene name phosphatidylinositol transfer protein, cytoplasmic 1
Gene symbol Pitpnc1
Other names/aliases 1110020B03Rik
5830436L09Rik
AI662802
AI851387
C330017I21Rik
Dnr411
RDGBB
RDGBB1
rdgB-beta
Species Mus musculus
 Database cross references - Pitpnc1
ExoCarta ExoCarta_71795
Entrez Gene 71795
UniProt Q8K4R4  
 Pitpnc1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Pitpnc1
Molecular Function
    lipid binding GO:0008289 IEA
    phosphatidylinositol transporter activity GO:0008526 ISO
Biological Process
    phosphatidylinositol metabolic process GO:0046488 ISO
    phospholipid transport GO:0015914 ISO
    lipid transport GO:0006869 IEA
    transport GO:0006810 IEA
Subcellular Localization
    nucleus GO:0005634 IEA
    intracellular GO:0005622 IEA
    cytoplasm GO:0005737 ISO
 Experiment description of studies that identified Pitpnc1 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Pitpnc1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Pitpnc1 is involved
No pathways found





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