Gene description for TRIO
Gene name	trio Rho guanine nucleotide exchange factor
Gene symbol	TRIO
Other names/aliases	ARHGEF23 tgat
Species	Homo sapiens
Database cross references - TRIO
ExoCarta	ExoCarta_7204
Entrez Gene	7204
HGNC	12303
MIM	601893
UniProt	O75962
TRIO identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723
Urine	22418980
Urine	22418980

Gene ontology annotations for TRIO

Molecular Function     protein serine/threonine kinase activity GO:0004674 IEA     Rho guanyl-nucleotide exchange factor activity GO:0005089 IEA     guanyl-nucleotide exchange factor activity GO:0005085 TAS     enzyme binding GO:0019899 IEA     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA Biological Process     positive regulation of apoptotic process GO:0043065 TAS     small GTPase mediated signal transduction GO:0007264 TAS     transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 TAS     apoptotic signaling pathway GO:0097190 TAS     neurotrophin TRK receptor signaling pathway GO:0048011 TAS     regulation of small GTPase mediated signal transduction GO:0051056 TAS     axon guidance GO:0007411 TAS     positive regulation of GTPase activity GO:0043547 TAS     protein phosphorylation GO:0006468 IEA Subcellular Localization     cytosol GO:0005829 TAS