Gene description for Cdhr5
Gene name cadherin-related family member 5
Gene symbol Cdhr5
Other names/aliases 1810074H01Rik
AI481143
Mucdhl
Mupcdh
Species Mus musculus
 Database cross references - Cdhr5
ExoCarta ExoCarta_72040
Vesiclepedia VP_72040
Entrez Gene 72040
UniProt Q8VHF2  
 Cdhr5 identified in sEVs derived from the following tissue/cell type
Faeces 33431899    
Faeces 33431899    
 Gene ontology annotations for Cdhr5
Molecular Function
    calcium ion binding GO:0005509 ISO
    calcium ion binding GO:0005509 ISS
    beta-catenin binding GO:0008013 ISO
    cell adhesion molecule binding GO:0050839 ISO
    cell adhesion molecule binding GO:0050839 ISS
Biological Process
    cell adhesion GO:0007155 IBA
    cell adhesion GO:0007155 ISO
    cell adhesion GO:0007155 ISS
    homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 IEA
    cell differentiation GO:0030154 IEA
    regulation of microvillus length GO:0032532 ISO
    regulation of microvillus length GO:0032532 ISS
    intermicrovillar adhesion GO:0090675 ISO
    intermicrovillar adhesion GO:0090675 ISS
    brush border assembly GO:1904970 ISO
Subcellular Localization
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 ISO
    plasma membrane GO:0005886 ISS
    microvillus GO:0005902 ISO
    clathrin-coated pit GO:0005905 ISO
    apical plasma membrane GO:0016324 ISO
    apical plasma membrane GO:0016324 ISS
    brush border membrane GO:0031526 ISO
    brush border membrane GO:0031526 ISS
    microvillus membrane GO:0031528 ISO
    microvillus membrane GO:0031528 ISS
 Experiment description of studies that identified Cdhr5 in sEVs
1
Experiment ID 303
MISEV standards
EM
Biophysical techniques
Cd63|Cd81|Cd9
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33431899    
Organism Mus musculus
Experiment description High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance
Authors "Kumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG."
Journal name Nat Commun
Publication year 2021
Sample Faeces
Sample name Intestinal epithelial cells - C57BL/6
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Lipid
miRNA
Methods used in the study Western blotting
Mass spectrometry
Immunofluorescence
miRNA array
HPLC
2
Experiment ID 304
MISEV standards
EM
Biophysical techniques
Cd63|Cd81|Cd9
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33431899    
Organism Mus musculus
Experiment description High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance
Authors "Kumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG."
Journal name Nat Commun
Publication year 2021
Sample Faeces
Sample name Intestinal epithelial cells - C57BL/6
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Lipid
miRNA
Methods used in the study Western blotting
Mass spectrometry
Immunofluorescence
miRNA array
HPLC
 Protein-protein interactions for Cdhr5
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Cdhr5 is involved
No pathways found





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