Gene description for Adipor1
Gene name adiponectin receptor 1
Gene symbol Adipor1
Other names/aliases 2810031L11Rik
ACDCR1
CGI-45
Paqr1
Species Mus musculus
 Database cross references - Adipor1
ExoCarta ExoCarta_72674
Vesiclepedia VP_72674
Entrez Gene 72674
UniProt Q91VH1  
 Adipor1 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Adipor1
Molecular Function
    protein binding GO:0005515 IPI
    protein kinase binding GO:0019901 IEA
    protein kinase binding GO:0019901 ISO
    signaling receptor activity GO:0038023 IBA
    signaling receptor activity GO:0038023 IDA
    identical protein binding GO:0042802 IDA
    metal ion binding GO:0046872 IEA
    adiponectin binding GO:0055100 IPI
    adiponectin binding GO:0055100 ISO
    adipokinetic hormone receptor activity GO:0097003 ISO
    adipokinetic hormone receptor activity GO:0097003 ISS
Biological Process
    hormone-mediated signaling pathway GO:0009755 ISO
    hormone-mediated signaling pathway GO:0009755 ISS
    negative regulation of epithelial cell migration GO:0010633 IEA
    negative regulation of epithelial cell migration GO:0010633 ISO
    negative regulation of epithelial to mesenchymal transition GO:0010719 IEA
    negative regulation of epithelial to mesenchymal transition GO:0010719 ISO
    regulation of glucose metabolic process GO:0010906 IMP
    regulation of lipid metabolic process GO:0019216 IMP
    fatty acid oxidation GO:0019395 ISO
    fatty acid oxidation GO:0019395 ISS
    negative regulation of cell growth GO:0030308 IEA
    negative regulation of cell growth GO:0030308 ISO
    leptin-mediated signaling pathway GO:0033210 IEA
    leptin-mediated signaling pathway GO:0033210 ISO
    adiponectin-activated signaling pathway GO:0033211 IBA
    adiponectin-activated signaling pathway GO:0033211 IDA
    adiponectin-activated signaling pathway GO:0033211 IMP
    adiponectin-activated signaling pathway GO:0033211 ISO
    glucose homeostasis GO:0042593 IMP
    negative regulation of receptor signaling pathway via JAK-STAT GO:0046426 IEA
    negative regulation of receptor signaling pathway via JAK-STAT GO:0046426 ISO
    positive regulation of receptor signaling pathway via JAK-STAT GO:0046427 IEA
    positive regulation of receptor signaling pathway via JAK-STAT GO:0046427 ISO
    positive regulation of insulin receptor signaling pathway GO:0046628 IEA
    positive regulation of insulin receptor signaling pathway GO:0046628 ISO
    positive regulation of cold-induced thermogenesis GO:0120162 IMP
    negative regulation of non-canonical NF-kappaB signal transduction GO:1901223 IEA
    negative regulation of non-canonical NF-kappaB signal transduction GO:1901223 ISO
Subcellular Localization
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IDA
    plasma membrane GO:0005886 ISO
    plasma membrane GO:0005886 ISS
 Experiment description of studies that identified Adipor1 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Adipor1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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