Gene description for Adipor1
Gene name adiponectin receptor 1
Gene symbol Adipor1
Other names/aliases 2810031L11Rik
ACDCR1
CGI-45
Paqr1
Species Mus musculus
 Database cross references - Adipor1
ExoCarta ExoCarta_72674
Entrez Gene 72674
UniProt Q91VH1  
 Adipor1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Adipor1
Molecular Function
    adiponectin binding GO:0055100 IPI
    protein binding GO:0005515 IPI
    receptor activity GO:0004872 IDA
    protein kinase binding GO:0019901 ISO
    protein heterodimerization activity GO:0046982 IPI
    hormone binding GO:0042562 ISS
    identical protein binding GO:0042802 IDA
Biological Process
    fatty acid oxidation GO:0019395 ISS
    positive regulation of insulin receptor signaling pathway GO:0046628 ISO
    positive regulation of JAK-STAT cascade GO:0046427 ISO
    lipid metabolic process GO:0006629 IEA
    hormone-mediated signaling pathway GO:0009755 ISS
    leptin-mediated signaling pathway GO:0033210 ISO
    negative regulation of cell growth GO:0030308 ISO
    adiponectin-activated signaling pathway GO:0033211 ISO
    fatty acid metabolic process GO:0006631 IEA
Subcellular Localization
    membrane GO:0016020 ISO
    integral component of membrane GO:0016021 IEA
    plasma membrane GO:0005886 ISO
 Experiment description of studies that identified Adipor1 in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Adipor1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Adipor1 is involved
No pathways found





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