Gene description for Rint1
Gene name RAD50 interactor 1
Gene symbol Rint1
Other names/aliases 1500019C06Rik
2810450M21Rik
Rint-1
Species Mus musculus
 Database cross references - Rint1
ExoCarta ExoCarta_72772
Vesiclepedia VP_72772
Entrez Gene 72772
UniProt Q8BZ36  
 Rint1 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Rint1
Biological Process
    endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888 IEA
    retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum GO:0006890 IBA
    retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum GO:0006890 IEA
    mitotic G2 DNA damage checkpoint signaling GO:0007095 ISO
    mitotic G2 DNA damage checkpoint signaling GO:0007095 ISS
    protein transport GO:0015031 IEA
    regulation of ER to Golgi vesicle-mediated transport GO:0060628 IBA
    regulation of ER to Golgi vesicle-mediated transport GO:0060628 IEA
    regulation of ER to Golgi vesicle-mediated transport GO:0060628 ISO
Subcellular Localization
    endoplasmic reticulum GO:0005783 ISO
    endoplasmic reticulum GO:0005783 ISS
    endoplasmic reticulum membrane GO:0005789 IEA
    Dsl1/NZR complex GO:0070939 IBA
    Dsl1/NZR complex GO:0070939 IEA
    Dsl1/NZR complex GO:0070939 ISO
 Experiment description of studies that identified Rint1 in sEVs
1
Experiment ID 15
MISEV standards
✔
EM
Biophysical techniques
✔
CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Rint1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Atg5  
Affinity Capture-RNA Mus musculus
2 Tmem173  
Proximity Label-MS Mus musculus
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here