Gene description for Wdr75
Gene name WD repeat domain 75
Gene symbol Wdr75
Other names/aliases 1300003A18Rik
2410118I19Rik
C77608
Species Mus musculus
 Database cross references - Wdr75
ExoCarta ExoCarta_73674
Entrez Gene 73674
 Wdr75 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Wdr75
Molecular Function
    poly(A) RNA binding GO:0044822 ISO
Biological Process
    regulation of mitochondrion degradation GO:1903146 ISO
    positive regulation of protein targeting to mitochondrion GO:1903955 ISO
Subcellular Localization
    nucleoplasm GO:0005654 ISO
 Experiment description of studies that identified Wdr75 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Wdr75
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Wdr75 is involved
No pathways found





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