Gene description for Ppp2r1b
Gene name protein phosphatase 2, regulatory subunit A, beta
Gene symbol Ppp2r1b
Other names/aliases 2410091N08Rik
AI790395
Species Mus musculus
 Database cross references - Ppp2r1b
ExoCarta ExoCarta_73699
Entrez Gene 73699
UniProt Q7TNP2  
 Ppp2r1b identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Ppp2r1b
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    apoptotic process involved in morphogenesis GO:0060561 ISO
    positive regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001241 ISO
Subcellular Localization
    membrane raft GO:0045121 ISO
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Ppp2r1b in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Ppp2r1b
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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