Gene description for Dppa3
Gene name developmental pluripotency-associated 3
Gene symbol Dppa3
Other names/aliases 2410075G02Rik
PCG7
PGC7
Stella
Species Mus musculus
 Database cross references - Dppa3
ExoCarta ExoCarta_73708
Vesiclepedia VP_73708
Entrez Gene 73708
UniProt Q8QZY3  
 Dppa3 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Dppa3
Molecular Function
    protein binding GO:0005515 IPI
    methylated histone binding GO:0035064 IBA
    methylated histone binding GO:0035064 IMP
Biological Process
    embryonic cleavage GO:0040016 IMP
    epigenetic programing of female pronucleus GO:0044726 IBA
    epigenetic programing of female pronucleus GO:0044726 IDA
    epigenetic programing of female pronucleus GO:0044726 IMP
Subcellular Localization
    chromatin GO:0000785 IDA
    female pronucleus GO:0001939 IDA
    male pronucleus GO:0001940 IDA
    male pronucleus GO:0001940 IDA
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleus GO:0005634 ISO
    nucleoplasm GO:0005654 TAS
    cytoplasm GO:0005737 IDA
    cytoplasm GO:0005737 ISO
    cytosol GO:0005829 TAS
 Experiment description of studies that identified Dppa3 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Dppa3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Dppa3 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here