Gene description for Dppa3
Gene name developmental pluripotency-associated 3
Gene symbol Dppa3
Other names/aliases 2410075G02Rik
PCG7
PGC7
Stella
Species Mus musculus
 Database cross references - Dppa3
ExoCarta ExoCarta_73708
Entrez Gene 73708
UniProt Q8QZY3  
 Dppa3 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Dppa3
Molecular Function
    protein binding GO:0005515 IPI
    methylated histone binding GO:0035064 IMP
Biological Process
    embryonic cleavage GO:0040016 IMP
    regulation of genetic imprinting GO:2000653 IMP
    chromatin modification GO:0016568 IEA
    multicellular organismal development GO:0007275 IEA
    negative regulation of DNA demethylation GO:1901536 IMP
    protection of DNA demethylation of female pronucleus GO:0044726 IMP
Subcellular Localization
    female pronucleus GO:0001939 IDA
    nucleus GO:0005634 IDA
    male pronucleus GO:0001940 IDA
    cytoplasm GO:0005737 IDA
 Experiment description of studies that identified Dppa3 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Dppa3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Dppa3 is involved
No pathways found





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