Gene description for Plce1
Gene name	phospholipase C, epsilon 1
Gene symbol	Plce1
Other names/aliases	4933403A21Rik PLCepsilon Plce mKIAA1516
Species	Mus musculus
Database cross references - Plce1
ExoCarta	ExoCarta_74055
Entrez Gene	74055
UniProt	Q8K4S1
Plce1 identified in exosomes derived from the following tissue/cell type
Basophilic leukemia cells	20424270
Mast cells	17486113

Gene ontology annotations for Plce1

Molecular Function     phosphoric diester hydrolase activity GO:0008081 IEA     hydrolase activity GO:0016787 IEA     phospholipase C activity GO:0004629 ISO     Ras GTPase binding GO:0017016 ISO     phosphatidylinositol phospholipase C activity GO:0004435 ISO     signal transducer activity GO:0004871 IEA     guanyl-nucleotide exchange factor activity GO:0005085 IEA     enzyme binding GO:0019899 ISO Biological Process     regulation of protein kinase activity GO:0045859 ISO     lipid catabolic process GO:0016042 IEA     regulation of G-protein coupled receptor protein signaling pathway GO:0008277 ISO     intracellular signal transduction GO:0035556 IEA     glomerulus development GO:0032835 ISO     Ras protein signal transduction GO:0007265 ISO     G-protein coupled receptor signaling pathway GO:0007186 ISO     small GTPase mediated signal transduction GO:0007264 IEA     lipid metabolic process GO:0006629 IEA     phospholipase C-activating G-protein coupled receptor signaling pathway GO:0007200 ISO     regulation of Ras protein signal transduction GO:0046578 ISO     activation of MAPK activity GO:0000187 ISO     signal transduction GO:0007165 IEA Subcellular Localization     Golgi apparatus GO:0005794 IEA     cytosol GO:0005829 ISO     cytoplasm GO:0005737 ISO     membrane GO:0016020 IEA     plasma membrane GO:0005886 ISO