Gene description for Dhcr24
Gene name	24-dehydrocholesterol reductase
Gene symbol	Dhcr24
Other names/aliases	2310076D10Rik 5830417J06Rik mKIAA0018
Species	Mus musculus
Database cross references - Dhcr24
ExoCarta	ExoCarta_74754
Vesiclepedia	VP_74754
Entrez Gene	74754
UniProt	Q8VCH6
Dhcr24 identified in sEVs derived from the following tissue/cell type
Neural stem cells	25242146

Gene ontology annotations for Dhcr24

Molecular Function     delta24(24-1) sterol reductase activity GO:0000246 IBA     delta24(24-1) sterol reductase activity GO:0000246 IEA     delta24(24-1) sterol reductase activity GO:0000246 ISO     oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor GO:0016628 ISO     enzyme binding GO:0019899 ISO     enzyme binding GO:0019899 ISS     peptide antigen binding GO:0042605 ISO     peptide antigen binding GO:0042605 ISS     delta24-sterol reductase activity GO:0050614 IEA     delta24-sterol reductase activity GO:0050614 ISO     FAD binding GO:0071949 IEA Biological Process     cholesterol biosynthetic process GO:0006695 IMP     cholesterol biosynthetic process GO:0006695 IMP     cholesterol biosynthetic process GO:0006695 ISO     Ras protein signal transduction GO:0007265 IEA     Ras protein signal transduction GO:0007265 ISO     protein localization GO:0008104 IMP     steroid metabolic process GO:0008202 IBA     steroid metabolic process GO:0008202 ISO     cholesterol metabolic process GO:0008203 IMP     negative regulation of cell population proliferation GO:0008285 IEA     negative regulation of cell population proliferation GO:0008285 ISO     response to hormone GO:0009725 IEA     tissue development GO:0009888 IMP     tissue development GO:0009888 ISO     tissue development GO:0009888 ISS     sterol metabolic process GO:0016125 IMP     male genitalia development GO:0030539 IMP     plasminogen activation GO:0031639 IMP     cholesterol biosynthetic process via desmosterol GO:0033489 IEA     cholesterol biosynthetic process via desmosterol GO:0033489 ISO     amyloid precursor protein catabolic process GO:0042987 IMP     skin development GO:0043588 IMP     membrane organization GO:0061024 IMP Subcellular Localization     Golgi membrane GO:0000139 IEA     nucleus GO:0005634 ISO     nucleus GO:0005634 ISS     cytoplasm GO:0005737 IBA     endoplasmic reticulum GO:0005783 ISO     endoplasmic reticulum GO:0005783 ISS     endoplasmic reticulum membrane GO:0005789 IEA