Gene description for Rprd2
Gene name regulation of nuclear pre-mRNA domain containing 2
Gene symbol Rprd2
Other names/aliases 2810036A19Rik
4930535B03Rik
6720469I21Rik
AL022841
AL022940
AU021304
BB077382
mKIAA0460
Species Mus musculus
 Database cross references - Rprd2
ExoCarta ExoCarta_75137
Vesiclepedia VP_75137
Entrez Gene 75137
UniProt Q6NXI6  
 Rprd2 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Rprd2
Molecular Function
    RNA polymerase II complex binding GO:0000993 IBA
    RNA polymerase II C-terminal domain binding GO:0099122 IEA
Biological Process
    mRNA 3'-end processing GO:0031124 IBA
Subcellular Localization
    transcription preinitiation complex GO:0097550 ISO
    transcription preinitiation complex GO:0097550 ISS
 Experiment description of studies that identified Rprd2 in sEVs
1
Experiment ID 15
MISEV standards
✔
EM
Biophysical techniques
✔
CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Rprd2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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