Gene description for Arxes1
Gene name adipocyte-related X-chromosome expressed sequence 1
Gene symbol Arxes1
Other names/aliases 6530401D17Rik
Spc22/23
Spcs3
Species Mus musculus
 Database cross references - Arxes1
ExoCarta ExoCarta_76219
Vesiclepedia VP_76219
Entrez Gene 76219
UniProt Q9D365  
 Arxes1 identified in sEVs derived from the following tissue/cell type
Neural stem cells 25242146    
 Gene ontology annotations for Arxes1
Biological Process
    signal peptide processing GO:0006465 IBA
    signal peptide processing GO:0006465 IEA
    protein targeting to ER GO:0045047 IBA
    fat cell differentiation GO:0045444 IMP
Subcellular Localization
    endoplasmic reticulum GO:0005783 IDA
    signal peptidase complex GO:0005787 IBA
    signal peptidase complex GO:0005787 IEA
 Experiment description of studies that identified Arxes1 in sEVs
1
Experiment ID 264
MISEV standards
Biophysical techniques
CD63|CD9
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25242146    
Organism Mus musculus
Experiment description Extracellular Vesicles from Neural Stem Cells Transfer IFN-? via Ifngr1 to Activate Stat1 Signaling in Target Cells
Authors "Chiara Cossetti, Nunzio Iraci, Tim R. Mercer, Tommaso Leonardi, Emanuele Alpi, Denise Drago, Clara Alfaro-Cervello, Harpreet K. Saini, Matthew P. Davis, Julia Schaeffer, Beatriz Vega, Matilde Stefanini, CongJian Zhao, Werner Muller, Jose Manuel Garcia-Verdugo, Suresh Mathivanan, Angela Bachi, Anton J. Enright, John S. Mattick, Stefano Pluchino"
Journal name Molecular Cell
Publication year 2014
Sample Neural stem cells
Sample name NPCs - Th2 treated
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.20 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Arxes1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Usp7  
Affinity Capture-MS Mus musculus
View the network image/svg+xml
 Pathways in which Arxes1 is involved
No pathways found





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