Gene description for Rab2b
Gene name RAB2B, member RAS oncogene family
Gene symbol Rab2b
Other names/aliases 1500012D09Rik
4930528G15Rik
A230002G14
D530043M21Rik
Species Mus musculus
 Database cross references - Rab2b
ExoCarta ExoCarta_76338
Entrez Gene 76338
UniProt P59279  
 Rab2b identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Rab2b
Molecular Function
    GTPase activity GO:0003924 IBA
    GTP binding GO:0005525 IEA
    nucleotide binding GO:0000166 IEA
Biological Process
    positive regulation of exocytosis GO:0045921 ISO
    vesicle-mediated transport GO:0016192 IEA
    intracellular protein transport GO:0006886 IBA
    Rab protein signal transduction GO:0032482 IBA
    small GTPase mediated signal transduction GO:0007264 IEA
    transport GO:0006810 IEA
    protein transport GO:0015031 IEA
Subcellular Localization
    endoplasmic reticulum membrane GO:0005789 IBA
    Golgi apparatus GO:0005794 IEA
    plasma membrane GO:0005886 IEA
    membrane GO:0016020 IEA
    extracellular exosome GO:0070062 ISO
    endoplasmic reticulum GO:0005783 IEA
    Golgi membrane GO:0000139 IBA
 Experiment description of studies that identified Rab2b in exosomes
1
Experiment ID 188
ISEV standards
EM
EV Biophysical techniques
GAPDH|UCHL1|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Rab2b
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SMAD4  
Affinity Capture-Luminescence Homo sapiens
View the network image/svg+xml
 Pathways in which Rab2b is involved
No pathways found





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