Gene description for AP3B1
Gene name adaptor-related protein complex 3, beta 1 subunit
Gene symbol AP3B1
Other names/aliases -
Species Bos taurus
 Database cross references - AP3B1
ExoCarta ExoCarta_767602
Entrez Gene 767602
UniProt Q32PG1  
 AP3B1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for AP3B1
Molecular Function
    GTP-dependent protein binding GO:0030742 IEA
    protein phosphatase binding GO:0019903 IEA
Biological Process
    blood coagulation GO:0007596 IEA
    protein targeting to lysosome GO:0006622 IEA
    positive regulation of NK T cell differentiation GO:0051138 IEA
    antigen processing and presentation, exogenous lipid antigen via MHC class Ib GO:0048007 IEA
    melanosome organization GO:0032438 IEA
    anterograde synaptic vesicle transport GO:0048490 ISS
    anterograde axon cargo transport GO:0008089 ISS
Subcellular Localization
    clathrin-coated vesicle membrane GO:0030665 IEA
    Golgi apparatus GO:0005794 IEA
    lysosomal membrane GO:0005765 IEA
    AP-3 adaptor complex GO:0030123 IEA
 Experiment description of studies that identified AP3B1 in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for AP3B1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which AP3B1 is involved
PathwayEvidenceSource
Golgi Associated Vesicle Biogenesis IEA Reactome





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