Gene description for C1S
Gene name complement component 1, s subcomponent
Gene symbol C1S
Other names/aliases -
Species Bos taurus
 Database cross references - C1S
ExoCarta ExoCarta_767827
Entrez Gene 767827
UniProt Q0VCX1  
 C1S identified in exosomes derived from the following tissue/cell type
Serum 19327352    
 Gene ontology annotations for C1S
Molecular Function
    serine-type endopeptidase activity GO:0004252 IEA
    calcium ion binding GO:0005509 IEA
Biological Process
    proteolysis GO:0006508 IEA
    innate immune response GO:0045087 IEA
    complement activation, classical pathway GO:0006958 IEA
Subcellular Localization
    extracellular region GO:0005576 IEA
 Experiment description of studies that identified C1S in exosomes
1
Experiment ID 187
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19327352    
Organism Bos taurus
Experiment description Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes.
Authors Ochieng J, Pratap S, Khatua AK, Sakwe AM.
Journal name Exp Cell Res
Publication year 2009
Sample Serum
Sample name Normal - Fetal bovine serum
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for C1S
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which C1S is involved
No pathways found





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