Gene description for UBE2L3
Gene name ubiquitin-conjugating enzyme E2L 3
Gene symbol UBE2L3
Other names/aliases -
Species Bos taurus
 Database cross references - UBE2L3
ExoCarta ExoCarta_767894
Entrez Gene 767894
UniProt Q3MHP1  
 UBE2L3 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for UBE2L3
Molecular Function
    transcription coactivator activity GO:0003713 ISS
    ligase activity GO:0016874 IEA
    ubiquitin-protein transferase activity GO:0004842 ISS
    ATP binding GO:0005524 IEA
Biological Process
    cell cycle phase transition GO:0044770 ISS
    transcription, DNA-templated GO:0006351 IEA
    cellular response to steroid hormone stimulus GO:0071383 ISS
    cellular response to glucocorticoid stimulus GO:0071385 ISS
    protein K11-linked ubiquitination GO:0070979 ISS
    cell proliferation GO:0008283 ISS
    regulation of transcription, DNA-templated GO:0006355 ISS
    protein polyubiquitination GO:0000209 ISS
    protein ubiquitination GO:0016567 ISS
Subcellular Localization
    nucleus GO:0005634 ISS
    cytoplasm GO:0005737 ISS
 Experiment description of studies that identified UBE2L3 in exosomes
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for UBE2L3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which UBE2L3 is involved
No pathways found

Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here