Gene description for FAF2
Gene name Fas associated factor family member 2
Gene symbol FAF2
Other names/aliases UBX8
UBXD8
Species Bos taurus
 Database cross references - FAF2
ExoCarta ExoCarta_767948
Entrez Gene 767948
UniProt Q2HJD0  
 FAF2 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for FAF2
Molecular Function
    ubiquitin protein ligase binding GO:0031625 IEA
    lipase inhibitor activity GO:0055102 IEA
    ubiquitin binding GO:0043130 IEA
    lipase binding GO:0035473 IEA
Biological Process
    negative regulation of catalytic activity GO:0043086 IEA
    response to unfolded protein GO:0006986 IEA
    lipid particle organization GO:0034389 IEA
    ER-associated ubiquitin-dependent protein catabolic process GO:0030433 ISS
Subcellular Localization
    lipid particle GO:0005811 IEA
    VCP-NPL4-UFD1 AAA ATPase complex GO:0034098 IEA
 Experiment description of studies that identified FAF2 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for FAF2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which FAF2 is involved
No pathways found





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