Gene description for Ddx10
Gene name DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
Gene symbol Ddx10
Other names/aliases 4632415A01Rik
AI646054
Species Mus musculus
 Database cross references - Ddx10
ExoCarta ExoCarta_77591
Entrez Gene 77591
UniProt Q80Y44  
 Ddx10 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Ddx10
Molecular Function
    nucleic acid binding GO:0003676 IEA
    RNA binding GO:0003723 IEA
    poly(A) RNA binding GO:0044822 ISO
    helicase activity GO:0004386 IEA
    nucleotide binding GO:0000166 IEA
    ATP binding GO:0005524 IEA
    hydrolase activity GO:0016787 IEA
    ATP-dependent RNA helicase activity GO:0004004 IBA
Biological Process
    biological_process GO:0008150 ND
    RNA secondary structure unwinding GO:0010501 IBA
Subcellular Localization
    cellular_component GO:0005575 ND
 Experiment description of studies that identified Ddx10 in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Ddx10
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ddx10 is involved
No pathways found





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