Gene description for PRPS1
Gene name phosphoribosyl pyrophosphate synthetase 1
Gene symbol PRPS1
Other names/aliases -
Species Bos taurus
 Database cross references - PRPS1
ExoCarta ExoCarta_781227
Vesiclepedia VP_781227
Entrez Gene 781227
UniProt Q2HJ58  
 PRPS1 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PRPS1
Molecular Function
    magnesium ion binding GO:0000287 IEA
    ribose phosphate diphosphokinase activity GO:0004749 IEA
    ATP binding GO:0005524 IEA
Biological Process
    5-phosphoribose 1-diphosphate biosynthetic process GO:0006015 IEA
    purine nucleotide biosynthetic process GO:0006164 IEA
    ribonucleoside monophosphate biosynthetic process GO:0009156 IEA
Subcellular Localization
    ribose phosphate diphosphokinase complex GO:0002189 IEA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified PRPS1 in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PRPS1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here