Gene description for PRPS1
Gene name phosphoribosyl pyrophosphate synthetase 1
Gene symbol PRPS1
Other names/aliases -
Species Bos taurus
 Database cross references - PRPS1
ExoCarta ExoCarta_781227
Entrez Gene 781227
UniProt Q2HJ58  
 PRPS1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PRPS1
Molecular Function
    kinase activity GO:0016301 IEA
    protein homodimerization activity GO:0042803 ISS
    ATP binding GO:0005524 ISS
    ribose phosphate diphosphokinase activity GO:0004749 ISS
    magnesium ion binding GO:0000287 IEA
Biological Process
    hypoxanthine biosynthetic process GO:0046101 IEA
    5-phosphoribose 1-diphosphate biosynthetic process GO:0006015 IEA
    phosphorylation GO:0016310 IEA
    urate biosynthetic process GO:0034418 IEA
    ribonucleoside monophosphate biosynthetic process GO:0009156 IEA
    purine nucleotide biosynthetic process GO:0006164 IEA
    nervous system development GO:0007399 IEA
 Experiment description of studies that identified PRPS1 in exosomes
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PRPS1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PRPS1 is involved
No pathways found

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