Gene description for CISD2
Gene name CDGSH iron sulfur domain 2
Gene symbol CISD2
Other names/aliases -
Species Bos taurus
 Database cross references - CISD2
ExoCarta ExoCarta_781260
Entrez Gene 781260
UniProt Q05B71  
 CISD2 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for CISD2
Molecular Function
    2 iron, 2 sulfur cluster binding GO:0051537 ISS
    poly(A) RNA binding GO:0044822 IEA
    protein homodimerization activity GO:0042803 ISS
    metal ion binding GO:0046872 IEA
Biological Process
    mitochondrion degradation GO:0000422 ISS
    multicellular organismal aging GO:0010259 ISS
    regulation of autophagy GO:0010506 ISS
Subcellular Localization
    endoplasmic reticulum membrane GO:0005789 ISS
    mitochondrial outer membrane GO:0005741 ISS
    integral component of membrane GO:0016021 IEA
    protein complex GO:0043234 IEA
 Experiment description of studies that identified CISD2 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CISD2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CISD2 is involved
No pathways found





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