Gene description for Hist3h2ba
Gene name histone cluster 3, H2ba
Gene symbol Hist3h2ba
Other names/aliases 1500011O09Rik
AI413321
Species Mus musculus
 Database cross references - Hist3h2ba
ExoCarta ExoCarta_78303
Entrez Gene 78303
UniProt Q9D2U9  
 Hist3h2ba identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
Oligodendrocytes 21136642    
 Gene ontology annotations for Hist3h2ba
Molecular Function
    protein heterodimerization activity GO:0046982 IEA
    DNA binding GO:0003677 IBA
Biological Process
    biological_process GO:0008150 ND
    nucleosome assembly GO:0006334 IBA
Subcellular Localization
    chromosome GO:0005694 IEA
    nucleus GO:0005634 ISO
    nuclear nucleosome GO:0000788 IBA
    extracellular exosome GO:0070062 ISO
    nucleosome GO:0000786 IEA
 Experiment description of studies that identified Hist3h2ba in exosomes
1
Experiment ID 210
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD81|FLOT1
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 33
ISEV standards
EM|IEM
EV Biophysical techniques
Alix|TSG101
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21136642    
Organism Mus musculus
Experiment description Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?
Authors Kramer-Albers EM, Bretz N, Tenzer S, Winterstein C, Mobius W, Berger H, Nave KA, Schild H, Trotter J
Journal name PROTEOMICS_CL
Publication year 2007
Sample Oligodendrocytes
Sample name Oligodendrocytes
Oli-neu
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for Hist3h2ba
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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