Gene description for LOC783680
Gene name beta-2-microglobulin
Gene symbol LOC783680
Other names/aliases B2M
Species Bos taurus
 Database cross references - LOC783680
ExoCarta ExoCarta_783680
Vesiclepedia VP_783680
Entrez Gene 783680
UniProt P01888  
 LOC783680 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for LOC783680
Molecular Function
    MHC class II protein complex binding GO:0023026 IEA
Biological Process
    immunoglobulin production involved in immunoglobulin-mediated immune response GO:0002381 IEA
    peptide antigen assembly with MHC class II protein complex GO:0002503 IEA
    immune response GO:0006955 IEA
    antigen processing and presentation of exogenous peptide antigen via MHC class II GO:0019886 IEA
    positive regulation of T cell activation GO:0050870 IEA
Subcellular Localization
    MHC class I protein complex GO:0042612 IEA
    MHC class II protein complex GO:0042613 IEA
 Experiment description of studies that identified LOC783680 in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for LOC783680
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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