Gene description for Tsc22d4
Gene name TSC22 domain family, member 4
Gene symbol Tsc22d4
Other names/aliases 0610009M14Rik
1700023B23Rik
AI415410
Thg-1pit
Tilz2
Species Mus musculus
 Database cross references - Tsc22d4
ExoCarta ExoCarta_78829
Vesiclepedia VP_78829
Entrez Gene 78829
UniProt Q9EQN3  
 Tsc22d4 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Tsc22d4
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 IMP
    response to osmotic stress GO:0006970 IDA
    glucose homeostasis GO:0042593 IMP
    neuron cellular homeostasis GO:0070050 IMP
    neuron projection extension GO:1990138 IMP
Subcellular Localization
    acrosomal vesicle GO:0001669 ISO
    nucleus GO:0005634 IDA
    cytoplasm GO:0005737 IDA
    dendrite GO:0030425 IDA
    synapse GO:0045202 IDA
 Experiment description of studies that identified Tsc22d4 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Tsc22d4
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Tlx3  
Two-hybrid Mus musculus
2 Kctd13  
Affinity Capture-MS Mus musculus
View the network image/svg+xml
 Pathways in which Tsc22d4 is involved
No pathways found





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