Gene description for Cacul1
Gene name CDK2 associated, cullin domain 1
Gene symbol Cacul1
Other names/aliases 2700078E11Rik
2810417M16Rik
9830127L17Rik
AI450346
D130033C15Rik
Species Mus musculus
 Database cross references - Cacul1
ExoCarta ExoCarta_78832
Vesiclepedia VP_78832
Entrez Gene 78832
UniProt Q8R0X2  
 Cacul1 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Cacul1
Molecular Function
    protein kinase binding GO:0019901 IBA
    protein kinase binding GO:0019901 IEA
    protein kinase binding GO:0019901 ISO
    ubiquitin protein ligase binding GO:0031625 IEA
Biological Process
    G1/S transition of mitotic cell cycle GO:0000082 IBA
    G1/S transition of mitotic cell cycle GO:0000082 ISO
    G1/S transition of mitotic cell cycle GO:0000082 ISS
    ubiquitin-dependent protein catabolic process GO:0006511 IEA
    positive regulation of cell population proliferation GO:0008284 ISO
    positive regulation of cell population proliferation GO:0008284 ISS
    positive regulation of protein kinase activity GO:0045860 ISO
    positive regulation of protein kinase activity GO:0045860 ISS
 Experiment description of studies that identified Cacul1 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Cacul1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Cacul1 is involved
No pathways found





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