Gene description for Gins3
Gene name GINS complex subunit 3 (Psf3 homolog)
Gene symbol Gins3
Other names/aliases 2700085M18Rik
AI616142
Species Mus musculus
 Database cross references - Gins3
ExoCarta ExoCarta_78833
Vesiclepedia VP_78833
Entrez Gene 78833
UniProt Q9CY94  
 Gins3 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Gins3
Molecular Function
    molecular_function GO:0003674 ND
Biological Process
    DNA replication GO:0006260 IMP
    DNA unwinding involved in DNA replication GO:0006268 ISO
    DNA unwinding involved in DNA replication GO:0006268 NAS
    embryo development GO:0009790 IMP
    multicellular organism growth GO:0035264 IMP
    cellular senescence GO:0090398 IMP
    mitotic DNA replication initiation GO:1902975 IBA
Subcellular Localization
    GINS complex GO:0000811 IBA
    GINS complex GO:0000811 ISO
    nucleus GO:0005634 ISO
    nucleus GO:0005634 NAS
    nucleoplasm GO:0005654 ISO
    CMG complex GO:0071162 ISO
    CMG complex GO:0071162 ISS
 Experiment description of studies that identified Gins3 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Gins3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Tmem173  
Proximity Label-MS Mus musculus
View the network image/svg+xml



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