Gene description for Asb15
Gene name ankyrin repeat and SOCS box-containing 15
Gene symbol Asb15
Other names/aliases 4930400E23Rik
Asb-15
Species Mus musculus
 Database cross references - Asb15
ExoCarta ExoCarta_78910
Vesiclepedia VP_78910
Entrez Gene 78910
UniProt Q8VHS6  
 Asb15 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Asb15
Molecular Function
    molecular_function GO:0003674 ND
    protein binding GO:0005515 IPI
    chloroplast targeting sequence binding GO:0030941 IBA
Biological Process
    biological_process GO:0008150 ND
    protein ubiquitination GO:0016567 IEA
    intracellular signal transduction GO:0035556 IEA
    protein targeting to chloroplast GO:0045036 IBA
    positive regulation of JNK cascade GO:0046330 IBA
    negative regulation of canonical Wnt signaling pathway GO:0090090 IBA
Subcellular Localization
    nucleus GO:0005634 IBA
 Experiment description of studies that identified Asb15 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Asb15
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Zfp275  
Two-hybrid Mus musculus
2 Pcbd1  
Two-hybrid Mus musculus
3 Tox3  
Two-hybrid Mus musculus
4 Zbtb39  
Two-hybrid Mus musculus
View the network image/svg+xml
 Pathways in which Asb15 is involved
No pathways found





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