Gene description for Asb15
Gene name ankyrin repeat and SOCS box-containing 15
Gene symbol Asb15
Other names/aliases 4930400E23Rik
Asb-15
Species Mus musculus
 Database cross references - Asb15
ExoCarta ExoCarta_78910
Vesiclepedia VP_78910
Entrez Gene 78910
UniProt Q8VHS6  
 Asb15 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Asb15
Molecular Function
    molecular_function GO:0003674 ND
Biological Process
    biological_process GO:0008150 ND
    intracellular signal transduction GO:0035556 IEA
Subcellular Localization
    cellular_component GO:0005575 ND
 Experiment description of studies that identified Asb15 in exosomes
1
Experiment ID 15
MISEV standards
✔
EM
EV Biophysical techniques
✔
CD63
EV Enriched markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Asb15
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Asb15 is involved
PathwayEvidenceSource
Antigen processing: Ubiquitination & Proteasome degradation IEA Reactome





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