Gene description for Mcam
Gene name melanoma cell adhesion molecule
Gene symbol Mcam
Other names/aliases CD146
Muc18
Species Rattus norvegicus
 Database cross references - Mcam
ExoCarta ExoCarta_78967
Entrez Gene 78967
UniProt Q9EPF2  
 Mcam identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Mcam
Molecular Function
    molecular_function GO:0003674 ND
Biological Process
    vascular wound healing GO:0061042 ISO
    positive regulation of cell migration GO:0030335 IDA
    cell adhesion GO:0007155 IEA
    glomerular filtration GO:0003094 ISO
    angiogenesis GO:0001525 ISO
Subcellular Localization
    external side of plasma membrane GO:0009897 ISO
    integral component of membrane GO:0016021 IEA
    nucleus GO:0005634 IDA
    perikaryon GO:0043204 IEA
    focal adhesion GO:0005925 ISO
    extracellular space GO:0005615 IDA
 Experiment description of studies that identified Mcam in exosomes
1
Experiment ID 225
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Mcam
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Mcam is involved
No pathways found





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