Gene description for Mcam
Gene name melanoma cell adhesion molecule
Gene symbol Mcam
Other names/aliases CD146
Muc18
Species Rattus norvegicus
 Database cross references - Mcam
ExoCarta ExoCarta_78967
Vesiclepedia VP_78967
Entrez Gene 78967
UniProt Q9EPF2  
 Mcam identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Mcam
Molecular Function
    laminin receptor activity GO:0005055 IBA
Biological Process
    angiogenesis GO:0001525 IBA
    angiogenesis GO:0001525 ISO
    glomerular filtration GO:0003094 ISO
    cell adhesion GO:0007155 IEA
    positive regulation of cell migration GO:0030335 IDA
    vascular wound healing GO:0061042 ISO
Subcellular Localization
    extracellular space GO:0005615 IDA
    plasma membrane GO:0005886 IBA
    external side of plasma membrane GO:0009897 ISO
    membrane GO:0016020 IEA
    perikaryon GO:0043204 IEA
 Experiment description of studies that identified Mcam in sEVs
1
Experiment ID 225
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Mcam
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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