Gene description for Fabp3
Gene name fatty acid binding protein 3, muscle and heart
Gene symbol Fabp3
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Fabp3
ExoCarta ExoCarta_79131
Entrez Gene 79131
UniProt P07483  
 Fabp3 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
Urine 20535238    
 Gene ontology annotations for Fabp3
Molecular Function
    icosatetraenoic acid binding GO:0050543 IPI
    long-chain fatty acid binding GO:0036041 ISO
    cytoskeletal protein binding GO:0008092 ISO
    oleic acid binding GO:0070538 ISO
    fatty acid binding GO:0005504 TAS
    long-chain fatty acid transporter activity GO:0005324 IPI
Biological Process
    long-chain fatty acid transport GO:0015909 IDA
    regulation of fatty acid oxidation GO:0046320 ISO
    phospholipid homeostasis GO:0055091 ISO
    response to fatty acid GO:0070542 IEP
    fatty acid beta-oxidation GO:0006635 NAS
    cholesterol homeostasis GO:0042632 ISO
    regulation of phosphatidylcholine biosynthetic process GO:2001245 ISO
    fatty acid metabolic process GO:0006631 IEP
    response to drug GO:0042493 IEP
    response to insulin GO:0032868 IEP
    long-chain fatty acid import GO:0044539 ISO
Subcellular Localization
    sarcoplasm GO:0016528 IDA
    extracellular exosome GO:0070062 ISO
    cytoplasm GO:0005737 IDA
    extracellular space GO:0005615 ISO
    sarcoplasmic reticulum GO:0016529 IDA
    cytosol GO:0005829 IDA
    mitochondrion GO:0005739 IDA
 Experiment description of studies that identified Fabp3 in exosomes
1
Experiment ID 225
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
2
Experiment ID 192
ISEV standards
CEM
EV Biophysical techniques
TSG101|HSP70
EV Cytosolic markers
CD63|CD81|FLOT
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20535238    
Organism Rattus norvegicus
Experiment description Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples.
Authors Conde-Vancells J, Rodriguez-Suarez E, Gonzalez E, Berisa A, Gil D, Embade N, Valle M, Luka Z, Elortza F, Wagner C, Lu SC, Mato JM, Falcon-Perez M.
Journal name Proteomics Clin Appl
Publication year 2010
Sample Urine
Sample name Urine - Rats of liver injury
Isolation/purification methods Differential centrifugation
Filtration
UltracentrifugationSucrose cushion
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Fabp3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Fabp3 is involved
PathwayEvidenceSource
Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis IEA Reactome





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