Gene description for Fabp3
Gene name fatty acid binding protein 3, muscle and heart
Gene symbol Fabp3
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Fabp3
ExoCarta ExoCarta_79131
Vesiclepedia VP_79131
Entrez Gene 79131
UniProt P07483  
 Fabp3 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
Urine 20535238    
 Gene ontology annotations for Fabp3
Molecular Function
    long-chain fatty acid transmembrane transporter activity GO:0005324 IPI
    fatty acid binding GO:0005504 IPI
    fatty acid binding GO:0005504 TAS
    cytoskeletal protein binding GO:0008092 ISO
    lipid binding GO:0008289 IEA
    long-chain fatty acid binding GO:0036041 IBA
    long-chain fatty acid binding GO:0036041 ISO
    icosatetraenoic acid binding GO:0050543 IPI
    oleic acid binding GO:0070538 ISO
Biological Process
    fatty acid metabolic process GO:0006631 IEP
    fatty acid beta-oxidation GO:0006635 NAS
    response to xenobiotic stimulus GO:0009410 IEP
    long-chain fatty acid transport GO:0015909 IBA
    long-chain fatty acid transport GO:0015909 IDA
    long-chain fatty acid transport GO:0015909 ISO
    intracellular lipid transport GO:0032365 ISO
    response to insulin GO:0032868 IEP
    cholesterol homeostasis GO:0042632 ISO
    regulation of fatty acid oxidation GO:0046320 ISO
    brown fat cell differentiation GO:0050873 ISO
    phospholipid homeostasis GO:0055091 ISO
    response to fatty acid GO:0070542 IEP
    positive regulation of long-chain fatty acid import into cell GO:0140214 ISO
    regulation of phosphatidylcholine biosynthetic process GO:2001245 ISO
Subcellular Localization
    extracellular space GO:0005615 ISO
    nucleus GO:0005634 IBA
    cytosol GO:0005829 IBA
    sarcoplasm GO:0016528 IDA
    sarcoplasmic reticulum GO:0016529 IDA
 Experiment description of studies that identified Fabp3 in exosomes
1
Experiment ID 225
MISEV standards
EM
Biophysical techniques
GAPDH|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
2
Experiment ID 192
MISEV standards
CEM
Biophysical techniques
TSG101|HSP70|CD63|CD81|FLOT
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20535238    
Organism Rattus norvegicus
Experiment description Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Gonzalez E, Berisa A, Gil D, Embade N, Valle M, Luka Z, Elortza F, Wagner C, Lu SC, Mato JM, Falcon-Perez M."
Journal name Proteomics Clin Appl
Publication year 2010
Sample Urine
Sample name Urine - Rats of liver injury
Isolation/purification methods Differential centrifugation
Filtration
UltracentrifugationSucrose cushion
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Fabp3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Fabp3 is involved
PathwayEvidenceSource
Metabolism IEA Reactome
Metabolism of lipids IEA Reactome
Triglyceride catabolism IEA Reactome
Triglyceride metabolism IEA Reactome





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