Gene description for Trim23
Gene name tripartite motif-containing 23
Gene symbol Trim23
Other names/aliases 6330516O20Rik
Species Mus musculus
 Database cross references - Trim23
ExoCarta ExoCarta_81003
Entrez Gene 81003
UniProt Q8BGX0  
 Trim23 identified in exosomes derived from the following tissue/cell type
Basophilic leukemia cells 20424270    
 Gene ontology annotations for Trim23
Molecular Function
    GDP binding GO:0019003 ISO
    identical protein binding GO:0042802 ISO
    tubulin-glycine ligase activity GO:0070738 IEA
    protein-glycine ligase activity, elongating GO:0070737 IEA
    ribosomal S6-glutamic acid ligase activity GO:0018169 IEA
    zinc ion binding GO:0008270 IEA
    protein-glycine ligase activity GO:0070735 IEA
    nucleotide binding GO:0000166 IEA
    ligase activity GO:0016874 IEA
    UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity GO:0008766 IEA
    ubiquitin-protein transferase activity GO:0004842 ISO
    tubulin-glutamic acid ligase activity GO:0070740 IEA
    protein-glycine ligase activity, initiating GO:0070736 IEA
    coenzyme F420-0 gamma-glutamyl ligase activity GO:0043773 IEA
    coenzyme F420-2 alpha-glutamyl ligase activity GO:0043774 IEA
    protein-glutamic acid ligase activity GO:0070739 IEA
    GTPase activity GO:0003924 ISO
    GTP binding GO:0005525 ISO
    metal ion binding GO:0046872 IEA
Biological Process
    protein ubiquitination GO:0016567 ISO
    protein ADP-ribosylation GO:0006471 ISO
    small GTPase mediated signal transduction GO:0007264 IEA
Subcellular Localization
    lysosomal membrane GO:0005765 ISO
    Golgi apparatus GO:0005794 IEA
    Golgi membrane GO:0000139 ISO
    nucleus GO:0005634 IDA
    membrane GO:0016020 IEA
    lysosome GO:0005764 IEA
    intracellular GO:0005622 IEA
    cytoplasm GO:0005737 IDA
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Trim23 in exosomes
Experiment ID 89
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20424270    
Organism Rattus norvegicus
Experiment description Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins.
Authors Subra C, Grand D, Laulagnier K, Stella A, Lambeau G, Paillasse M, De Medina P, Monsarrat B, Perret B, Silvente-Poirot S, Poirot M, Record M.
Journal name JLR
Publication year 2010
Sample Basophilic leukemia cells
Sample name RBL-2H3
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Gas chromatography
Thin layer chromatography
Mass spectrometry [Qstar XL]
 Protein-protein interactions for Trim23
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Narg1  
Reconstituted Complex Mus musculus
View the network image/svg+xml
 Pathways in which Trim23 is involved
No pathways found

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