Gene description for Lat
Gene name	linker for activation of T cells
Gene symbol	Lat
Other names/aliases	-
Species	Rattus norvegicus
Database cross references - Lat
ExoCarta	ExoCarta_81511
Vesiclepedia	VP_81511
Entrez Gene	81511
UniProt	O70601
Lat identified in sEVs derived from the following tissue/cell type
Pancreatic cancer cells	20124479
Pancreatic cancer cells	20124479

Gene ontology annotations for Lat

Molecular Function     protein kinase binding GO:0019901 IBA     protein kinase binding GO:0019901 ISO     signaling receptor complex adaptor activity GO:0030159 ISO     signaling adaptor activity GO:0035591 ISO     molecular condensate scaffold activity GO:0140693 ISO Biological Process     adaptive immune response GO:0002250 IEA     lymphocyte homeostasis GO:0002260 ISO     inflammatory response GO:0006954 IBA     inflammatory response GO:0006954 ISO     immune response GO:0006955 IBA     immune response GO:0006955 ISO     signal transduction GO:0007165 IEA     integrin-mediated signaling pathway GO:0007229 ISO     Ras protein signal transduction GO:0007265 ISO     gene expression GO:0010467 ISO     calcium-mediated signaling GO:0019722 ISO     membrane raft distribution GO:0031580 ISO     intracellular signal transduction GO:0035556 IBA     intracellular signal transduction GO:0035556 ISO     mast cell degranulation GO:0043303 IEA     positive regulation of MAPK cascade GO:0043410 ISO     positive regulation of protein kinase activity GO:0045860 ISO     homeostasis of number of cells GO:0048872 ISO     T cell receptor signaling pathway GO:0050852 ISO     regulation of T cell activation GO:0050863 IBA     regulation of T cell activation GO:0050863 ISO Subcellular Localization     immunological synapse GO:0001772 IBA     immunological synapse GO:0001772 ISO     Golgi apparatus GO:0005794 ISO     plasma membrane GO:0005886 ISO     plasma membrane GO:0005886 ISO     cell-cell junction GO:0005911 ISO     COP9 signalosome GO:0008180 ISO     COP9 signalosome GO:0008180 ISS     membrane GO:0016020 IEA     membrane GO:0016020 ISO     TCR signalosome GO:0036398 ISO