Gene description for Acta2
Gene name	actin, alpha 2, smooth muscle, aorta
Gene symbol	Acta2
Other names/aliases	-
Species	Rattus norvegicus
Database cross references - Acta2
ExoCarta	ExoCarta_81633
Vesiclepedia	VP_81633
Entrez Gene	81633
UniProt	P62738
Acta2 identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Acta2

Molecular Function     ATP binding GO:0005524 IEA     hydrolase activity GO:0016787 IEA     protein kinase binding GO:0019901 IEA     protein kinase binding GO:0019901 ISO Biological Process     muscle contraction GO:0006936 IDA     regulation of blood pressure GO:0008217 IEA     regulation of blood pressure GO:0008217 ISO     response to virus GO:0009615 IEA     response to virus GO:0009615 ISO     positive regulation of gene expression GO:0010628 ISS     vascular associated smooth muscle contraction GO:0014829 IEA     vascular associated smooth muscle contraction GO:0014829 ISO     positive regulation of hepatic stellate cell migration GO:0061870 IMP     positive regulation of hepatic stellate cell contraction GO:0061874 IMP     positive regulation of ERK1 and ERK2 cascade GO:0070374 IMP     cellular response to transforming growth factor beta stimulus GO:0071560 IEP     juxtaglomerular apparatus development GO:0072051 IEP     glomerular mesangial cell development GO:0072144 IEA     glomerular mesangial cell development GO:0072144 ISO     mesenchyme migration GO:0090131 ISS     positive regulation of hepatic stellate cell activation GO:2000491 IMP Subcellular Localization     stress fiber GO:0001725 IDA     basement membrane GO:0005604 IDA     cytoplasm GO:0005737 ISO     cytoplasm GO:0005737 ISS     cytoskeleton GO:0005856 ISO     actin cytoskeleton GO:0015629 IBA     actin cytoskeleton GO:0015629 IDA     actin cytoskeleton GO:0015629 IEA     actin cytoskeleton GO:0015629 ISO     lamellipodium GO:0030027 ISS     filopodium GO:0030175 ISS     smooth muscle contractile fiber GO:0030485 IEA     smooth muscle contractile fiber GO:0030485 ISO     motile cilium GO:0031514 IEA     motile cilium GO:0031514 ISO     protein-containing complex GO:0032991 IEA     protein-containing complex GO:0032991 ISO     cell body GO:0044297 ISS