Gene description for Jup
Gene name	junction plakoglobin
Gene symbol	Jup
Other names/aliases	-
Species	Rattus norvegicus
Database cross references - Jup
ExoCarta	ExoCarta_81679
Vesiclepedia	VP_81679
Entrez Gene	81679
UniProt	Q6P0K8
Jup identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046

Gene ontology annotations for Jup

Molecular Function     transcription coactivator activity GO:0003713 IBA     transcription coactivator activity GO:0003713 IEA     transcription coactivator activity GO:0003713 ISO     protein binding GO:0005515 IPI     nuclear receptor binding GO:0016922 IBA     protein kinase binding GO:0019901 IPI     protein phosphatase binding GO:0019903 IBA     protein phosphatase binding GO:0019903 IEA     protein phosphatase binding GO:0019903 ISO     protein-containing complex binding GO:0044877 IPI     alpha-catenin binding GO:0045294 IBA     alpha-catenin binding GO:0045294 IEA     alpha-catenin binding GO:0045294 ISO     cadherin binding GO:0045296 IBA     cadherin binding GO:0045296 IEA     cadherin binding GO:0045296 ISO     cell adhesion molecule binding GO:0050839 ISO     cytoskeletal protein-membrane anchor activity GO:0106006 IEA     cytoskeletal protein-membrane anchor activity GO:0106006 ISO     protein tyrosine kinase binding GO:1990782 IPI Biological Process     positive regulation of cell-matrix adhesion GO:0001954 IEA     positive regulation of cell-matrix adhesion GO:0001954 ISO     desmosome assembly GO:0002159 IEA     desmosome assembly GO:0002159 ISO     desmosome assembly GO:0002159 ISO     cell adhesion GO:0007155 ISO     cell migration GO:0016477 IEA     cell migration GO:0016477 ISO     regulation of cell population proliferation GO:0042127 IEA     regulation of cell population proliferation GO:0042127 ISO     positive regulation of protein import into nucleus GO:0042307 IEA     positive regulation of protein import into nucleus GO:0042307 ISO     negative regulation of blood vessel endothelial cell migration GO:0043537 IEA     negative regulation of blood vessel endothelial cell migration GO:0043537 ISO     skin development GO:0043588 IEA     skin development GO:0043588 ISO     positive regulation of angiogenesis GO:0045766 IEA     positive regulation of angiogenesis GO:0045766 ISO     positive regulation of DNA-templated transcription GO:0045893 IEA     positive regulation of transcription by RNA polymerase II GO:0045944 IBA     detection of mechanical stimulus GO:0050982 IEA     detection of mechanical stimulus GO:0050982 ISO     positive regulation of DNA-binding transcription factor activity GO:0051091 ISO     canonical Wnt signaling pathway GO:0060070 IBA     cellular response to indole-3-methanol GO:0071681 IEA     cellular response to indole-3-methanol GO:0071681 ISO     protein localization to plasma membrane GO:0072659 IEA     protein localization to plasma membrane GO:0072659 ISO     bundle of His cell-Purkinje myocyte adhesion involved in cell communication GO:0086073 IEA     bundle of His cell-Purkinje myocyte adhesion involved in cell communication GO:0086073 ISO     regulation of heart rate by cardiac conduction GO:0086091 IEA     regulation of heart rate by cardiac conduction GO:0086091 ISO     cell-cell adhesion GO:0098609 IBA     cell-cell adhesion GO:0098609 ISO     cell-cell adhesion GO:0098609 ISO     regulation of ventricular cardiac muscle cell action potential GO:0098911 IEA     regulation of ventricular cardiac muscle cell action potential GO:0098911 ISO Subcellular Localization     cornified envelope GO:0001533 IEA     cornified envelope GO:0001533 ISO     nucleus GO:0005634 IBA     nucleus GO:0005634 ISO     cytoplasm GO:0005737 IBA     cytoplasm GO:0005737 ISO     cytosol GO:0005829 IEA     cytosol GO:0005829 ISO     intermediate filament GO:0005882 IEA     intermediate filament GO:0005882 ISO     plasma membrane GO:0005886 ISO     cell-cell junction GO:0005911 IDA     cell-cell junction GO:0005911 ISO     adherens junction GO:0005912 IBA     adherens junction GO:0005912 IDA     adherens junction GO:0005912 IEA     adherens junction GO:0005912 ISO     fascia adherens GO:0005916 IDA     cytoplasmic side of plasma membrane GO:0009898 IDA     intercalated disc GO:0014704 IEA     intercalated disc GO:0014704 ISO     actin cytoskeleton GO:0015629 IDA     apicolateral plasma membrane GO:0016327 IDA     lateral plasma membrane GO:0016328 IDA     catenin complex GO:0016342 IBA     catenin complex GO:0016342 IEA     catenin complex GO:0016342 ISO     Z disc GO:0030018 IEA     Z disc GO:0030018 ISO     desmosome GO:0030057 IDA     desmosome GO:0030057 IEA     desmosome GO:0030057 ISO     protein-DNA complex GO:0032993 IEA     protein-DNA complex GO:0032993 ISO     gamma-catenin-TCF7L2 complex GO:0071665 IEA     gamma-catenin-TCF7L2 complex GO:0071665 ISO