Gene description for Mif
Gene name	macrophage migration inhibitory factor (glycosylation-inhibiting factor)
Gene symbol	Mif
Other names/aliases	-
Species	Rattus norvegicus
Database cross references - Mif
ExoCarta	ExoCarta_81683
Vesiclepedia	VP_81683
Entrez Gene	81683
UniProt	P30904
Mif identified in exosomes derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046
Urine	20535238

Gene ontology annotations for Mif

Molecular Function     protease binding GO:0002020 ISO     dopachrome isomerase activity GO:0004167 ISO     dopachrome isomerase activity GO:0004167 ISS     cytokine activity GO:0005125 IBA     cytokine activity GO:0005125 IEA     cytokine activity GO:0005125 ISO     cytokine receptor binding GO:0005126 ISO     isomerase activity GO:0016853 IEA     chemoattractant activity GO:0042056 ISO     identical protein binding GO:0042802 ISO     protein-containing complex binding GO:0044877 IDA     phenylpyruvate tautomerase activity GO:0050178 IBA     phenylpyruvate tautomerase activity GO:0050178 ISO Biological Process     prostaglandin biosynthetic process GO:0001516 ISO     positive regulation of cytokine production GO:0001819 ISO     positive regulation of protein phosphorylation GO:0001934 ISO     hair follicle development GO:0001942 IEP     brain renin-angiotensin system GO:0002035 IMP     positive regulation of acute inflammatory response GO:0002675 IMP     negative regulation of mature B cell apoptotic process GO:0002906 ISO     inflammatory response GO:0006954 IEA     signal transduction GO:0007165 IEA     cell surface receptor signaling pathway GO:0007166 ISO     spermatogenesis GO:0007283 IMP     positive regulation of cell population proliferation GO:0008284 ISO     response to xenobiotic stimulus GO:0009410 IEP     response to mechanical stimulus GO:0009612 IEP     response to hormone GO:0009725 IEP     negative regulation of gene expression GO:0010629 ISO     negative regulation of macrophage chemotaxis GO:0010760 ISO     positive regulation of smooth muscle cell migration GO:0014911 IMP     carboxylic acid metabolic process GO:0019752 ISO     DNA damage response, signal transduction by p53 class mediator GO:0030330 ISO     negative regulation of cell migration GO:0030336 ISO     positive regulation of B cell proliferation GO:0030890 ISO     positive regulation of lipopolysaccharide-mediated signaling pathway GO:0031666 ISO     response to estradiol GO:0032355 IEP     response to lipopolysaccharide GO:0032496 IEP     response to progesterone GO:0032570 IEP     response to menaquinone GO:0032572 IEP     positive regulation of tumor necrosis factor production GO:0032760 ISO     response to insulin GO:0032868 IEP     negative regulation of myeloid cell apoptotic process GO:0033033 ISO     response to vitamin E GO:0033197 IEP     regulation of cell population proliferation GO:0042127 ISO     positive regulation of phosphorylation GO:0042327 ISO     drinking behavior GO:0042756 IMP     negative regulation of apoptotic process GO:0043066 ISO     positive regulation of potassium ion transport GO:0043268 IMP     positive regulation of MAP kinase activity GO:0043406 ISO     negative regulation of DNA damage response, signal transduction by p53 class mediator GO:0043518 ISO     skin development GO:0043588 IEP     innate immune response GO:0045087 IEA     positive regulation of glycolytic process GO:0045821 IMP     positive regulation of D-glucose import GO:0046326 IMP     positive regulation of fibroblast proliferation GO:0048146 ISO     positive regulation of axon regeneration GO:0048680 IMP     positive regulation of immune response GO:0050778 IMP     positive chemotaxis GO:0050918 IEA     negative regulation of protein metabolic process GO:0051248 ISO     response to glucocorticoid GO:0051384 IEP     positive regulation of prostaglandin secretion involved in immune response GO:0061078 ISO     positive regulation of myeloid leukocyte cytokine production involved in immune response GO:0061081 ISO     protein homotrimerization GO:0070207 ISO     cellular response to hydrogen peroxide GO:0070301 IEP     positive regulation of ERK1 and ERK2 cascade GO:0070374 ISO     cellular response to hypoxia GO:0071456 IEP     positive regulation of arachidonate secretion GO:0090238 ISO     cellular senescence GO:0090398 ISO     positive regulation of cAMP/PKA signal transduction GO:0141163 ISO     negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator GO:1902166 ISO     positive regulation of chemokine (C-X-C motif) ligand 2 production GO:2000343 ISO     negative regulation of cellular senescence GO:2000773 ISO Subcellular Localization     extracellular region GO:0005576 ISO     extracellular space GO:0005615 IBA     extracellular space GO:0005615 IDA     extracellular space GO:0005615 IEA     extracellular space GO:0005615 ISO     nucleoplasm GO:0005654 ISO     cytoplasm GO:0005737 ISO     cytosol GO:0005829 ISO     plasma membrane GO:0005886 ISO     cell surface GO:0009986 ISO