Gene description for AMN
Gene name amnion associated transmembrane protein
Gene symbol AMN
Other names/aliases PRO1028
amnionless
Species Homo sapiens
 Database cross references - AMN
ExoCarta ExoCarta_81693
Vesiclepedia VP_81693
Entrez Gene 81693
HGNC 14604
MIM 605799
UniProt Q9BXJ7  
 AMN identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for AMN
Molecular Function
    receptor binding GO:0005102 IPI
Biological Process
    small molecule metabolic process GO:0044281 TAS
    cobalamin metabolic process GO:0009235 TAS
    multicellular organismal development GO:0007275 IEA
    receptor-mediated endocytosis GO:0006898 IMP
    lipoprotein metabolic process GO:0042157 TAS
    excretion GO:0007588 IEA
    water-soluble vitamin metabolic process GO:0006767 TAS
    cobalamin transport GO:0015889 IDA
    vitamin metabolic process GO:0006766 TAS
    Golgi to plasma membrane protein transport GO:0043001 IDA
Subcellular Localization
    apical plasma membrane GO:0016324 IDA
    integral component of membrane GO:0016021 IEA
    extracellular space GO:0005615 IDA
    endocytic vesicle GO:0030139 IDA
    plasma membrane GO:0005886 TAS
    endosome membrane GO:0010008 TAS
    extracellular exosome GO:0070062 IDA
 Experiment description of studies that identified AMN in exosomes
1
Experiment ID 63
MISEV standards
✘ EV Biophysical techniques
✔
AQP2
EV Enriched markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for AMN
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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