Gene description for AMN
Gene name amnion associated transmembrane protein
Gene symbol AMN
Other names/aliases PRO1028
amnionless
Species Homo sapiens
 Database cross references - AMN
ExoCarta ExoCarta_81693
Vesiclepedia VP_81693
Entrez Gene 81693
HGNC 14604
MIM 605799
UniProt Q9BXJ7  
 AMN identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for AMN
Molecular Function
    signaling receptor binding GO:0005102 IPI
    protein binding GO:0005515 IPI
    cargo receptor activity GO:0038024 IDA
Biological Process
    receptor-mediated endocytosis GO:0006898 IBA
    receptor-mediated endocytosis GO:0006898 IDA
    receptor-mediated endocytosis GO:0006898 IMP
    protein localization GO:0008104 IBA
    cobalamin metabolic process GO:0009235 IDA
    cobalamin transport GO:0015889 IDA
    Golgi to plasma membrane protein transport GO:0043001 IDA
    renal protein absorption GO:0097017 IEA
Subcellular Localization
    extracellular space GO:0005615 IDA
    plasma membrane GO:0005886 TAS
    clathrin-coated pit GO:0005905 IEA
    endosome membrane GO:0010008 IEA
    membrane GO:0016020 IDA
    apical plasma membrane GO:0016324 IBA
    apical plasma membrane GO:0016324 IDA
    apical plasma membrane GO:0016324 NAS
    endocytic vesicle GO:0030139 IBA
    endocytic vesicle GO:0030139 IDA
    brush border membrane GO:0031526 IEA
    microvillus membrane GO:0031528 IDA
    receptor complex GO:0043235 IPI
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified AMN in exosomes
1
Experiment ID 63
MISEV standards
Biophysical techniques
AQP2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for AMN
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 STAMBP 10617
Two-hybrid Homo sapiens
View the network image/svg+xml



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