Gene description for Renbp
Gene name renin binding protein
Gene symbol Renbp
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Renbp
ExoCarta ExoCarta_81759
Entrez Gene 81759
UniProt P51607  
 Renbp identified in exosomes derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Renbp
Molecular Function
    protein homodimerization activity GO:0042803 IMP
    purine nucleotide binding GO:0017076 IDA
    ATP binding GO:0005524 IDA
    enzyme inhibitor activity GO:0004857 IDA
    endopeptidase inhibitor activity GO:0004866 IBA
    N-acylglucosamine 2-epimerase activity GO:0050121 ISO
Biological Process
    negative regulation of endopeptidase activity GO:0010951 IDA
    negative regulation of catalytic activity GO:0043086 IDA
    N-acetylmannosamine metabolic process GO:0006051 IDA
    N-acetylneuraminate catabolic process GO:0019262 IEA
    N-acetylglucosamine metabolic process GO:0006044 ISO
Subcellular Localization
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Renbp in exosomes
1
Experiment ID 35
ISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
CD81|CD63
EV Membrane markers
✔
HSPA5
EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Renbp
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Renbp is involved
No pathways found





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