Gene description for Renbp
Gene name renin binding protein
Gene symbol Renbp
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Renbp
ExoCarta ExoCarta_81759
Vesiclepedia VP_81759
Entrez Gene 81759
UniProt P51607  
 Renbp identified in sEVs derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Renbp
Molecular Function
    enzyme inhibitor activity GO:0004857 IDA
    ATP binding GO:0005524 IDA
    isomerase activity GO:0016853 IEA
    purine nucleotide binding GO:0017076 IDA
    peptidase inhibitor activity GO:0030414 IBA
    peptidase inhibitor activity GO:0030414 IEA
    peptidase inhibitor activity GO:0030414 ISO
    peptidase inhibitor activity GO:0030414 ISS
    identical protein binding GO:0042802 IDA
    identical protein binding GO:0042802 IEA
    identical protein binding GO:0042802 IMP
    identical protein binding GO:0042802 IPI
    identical protein binding GO:0042802 ISO
    N-acylglucosamine 2-epimerase activity GO:0050121 IBA
    N-acylglucosamine 2-epimerase activity GO:0050121 IDA
    N-acylglucosamine 2-epimerase activity GO:0050121 IEA
    N-acylglucosamine 2-epimerase activity GO:0050121 IMP
    N-acylglucosamine 2-epimerase activity GO:0050121 ISO
Biological Process
    carbohydrate metabolic process GO:0005975 IEA
    N-acetylglucosamine metabolic process GO:0006044 IBA
    N-acetylglucosamine metabolic process GO:0006044 IDA
    N-acetylglucosamine metabolic process GO:0006044 ISO
    N-acetylmannosamine metabolic process GO:0006051 IBA
    N-acetylmannosamine metabolic process GO:0006051 IDA
    negative regulation of endopeptidase activity GO:0010951 IDA
    N-acetylneuraminate catabolic process GO:0019262 IEA
    negative regulation of catalytic activity GO:0043086 IDA
 Experiment description of studies that identified Renbp in sEVs
1
Experiment ID 35
MISEV standards
CEM
Biophysical techniques
TSG101|Alix|CD81|CD63
Enriched markers
HSPA5
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM"
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Renbp
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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