Gene description for S100a10
Gene name S100 calcium binding protein A10
Gene symbol S100a10
Other names/aliases p11
Species Rattus norvegicus
 Database cross references - S100a10
ExoCarta ExoCarta_81778
Vesiclepedia VP_81778
Entrez Gene 81778
UniProt P05943  
 S100a10 identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for S100a10
Molecular Function
    calcium ion binding GO:0005509 IBA
    calcium ion binding GO:0005509 IEA
    protein binding GO:0005515 IPI
    lipid binding GO:0008289 ISO
    protein homodimerization activity GO:0042803 IEA
    protein homodimerization activity GO:0042803 ISO
    transmembrane transporter binding GO:0044325 IBA
    transmembrane transporter binding GO:0044325 IEA
    transmembrane transporter binding GO:0044325 ISO
    calcium-dependent protein binding GO:0048306 IBA
Biological Process
    regulation of cell growth GO:0001558 NAS
    membrane raft assembly GO:0001765 IEA
    membrane raft assembly GO:0001765 ISO
    vesicle budding from membrane GO:0006900 IEA
    vesicle budding from membrane GO:0006900 ISO
    response to xenobiotic stimulus GO:0009410 IEP
    positive regulation of plasminogen activation GO:0010756 IEA
    positive regulation of plasminogen activation GO:0010756 ISO
    mRNA transcription by RNA polymerase II GO:0042789 ISO
    positive regulation of GTPase activity GO:0043547 ISO
    regulation of cell differentiation GO:0045595 NAS
    positive regulation of transcription by RNA polymerase II GO:0045944 ISO
    regulation of neurogenesis GO:0050767 ISO
    positive regulation of stress fiber assembly GO:0051496 IEA
    positive regulation of stress fiber assembly GO:0051496 ISO
    positive regulation of focal adhesion assembly GO:0051894 IEA
    positive regulation of focal adhesion assembly GO:0051894 ISO
    protein localization to plasma membrane GO:0072659 IEA
    protein localization to plasma membrane GO:0072659 ISO
    positive regulation of substrate adhesion-dependent cell spreading GO:1900026 IEA
    positive regulation of substrate adhesion-dependent cell spreading GO:1900026 ISO
Subcellular Localization
    cytoplasm GO:0005737 IBA
    plasma membrane GO:0005886 ISO
    cell surface GO:0009986 ISO
    membrane GO:0016020 IEA
    membrane raft GO:0045121 IEA
    membrane raft GO:0045121 ISO
    RNA polymerase II transcription regulator complex GO:0090575 ISO
    plasma membrane protein complex GO:0098797 IEA
    plasma membrane protein complex GO:0098797 ISO
    AnxA2-p11 complex GO:1990665 IEA
    AnxA2-p11 complex GO:1990665 ISO
 Experiment description of studies that identified S100a10 in sEVs
1
Experiment ID 225
MISEV standards
EM
Biophysical techniques
GAPDH|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for S100a10
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which S100a10 is involved
PathwayEvidenceSource
Dissolution of Fibrin Clot IEA Reactome
Hemostasis IEA Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here