Gene description for Ugdh
Gene name UDP-glucose 6-dehydrogenase
Gene symbol Ugdh
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Ugdh
ExoCarta ExoCarta_83472
Vesiclepedia VP_83472
Entrez Gene 83472
UniProt O70199  
 Ugdh identified in sEVs derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Ugdh
Molecular Function
    UDP-glucose 6-dehydrogenase activity GO:0003979 IDA
    UDP-glucose 6-dehydrogenase activity GO:0003979 IEA
    UDP-glucose 6-dehydrogenase activity GO:0003979 ISO
    identical protein binding GO:0042802 ISO
    NAD binding GO:0051287 IEA
Biological Process
    gastrulation with mouth forming second GO:0001702 IEA
    gastrulation with mouth forming second GO:0001702 ISO
    gastrulation with mouth forming second GO:0001702 ISO
    gastrulation with mouth forming second GO:0001702 ISS
    glycosaminoglycan biosynthetic process GO:0006024 IBA
    UDP-glucuronate biosynthetic process GO:0006065 IEA
    UDP-glucuronate biosynthetic process GO:0006065 ISO
    UDP-glucuronate biosynthetic process GO:0006065 ISS
    heparan sulfate proteoglycan biosynthetic process GO:0015012 IEA
    heparan sulfate proteoglycan biosynthetic process GO:0015012 ISO
    heparan sulfate proteoglycan biosynthetic process GO:0015012 ISS
    chondroitin sulfate biosynthetic process GO:0030206 IEA
    chondroitin sulfate biosynthetic process GO:0030206 ISO
    chondroitin sulfate biosynthetic process GO:0030206 ISS
    protein hexamerization GO:0034214 ISO
    protein hexamerization GO:0034214 ISS
    neuron development GO:0048666 ISO
    neuron development GO:0048666 ISS
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleoplasm GO:0005654 ISO
 Experiment description of studies that identified Ugdh in sEVs
1
Experiment ID 35
MISEV standards
CEM
Biophysical techniques
TSG101|Alix|CD81|CD63
Enriched markers
HSPA5
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM"
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Ugdh
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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