Gene description for Bicc1
Gene name bicaudal C homolog 1 (Drosophila)
Gene symbol Bicc1
Other names/aliases Bic-C
bpk
jcpk
Species Mus musculus
 Database cross references - Bicc1
ExoCarta ExoCarta_83675
Entrez Gene 83675
UniProt Q99MQ1  
 Bicc1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Bicc1
Molecular Function
    nucleic acid binding GO:0003676 IEA
    protein binding GO:0005515 IPI
    poly(A) RNA binding GO:0044822 ISO
    RNA binding GO:0003723 ISA
Biological Process
    negative regulation of canonical Wnt signaling pathway GO:0090090 ISO
    multicellular organismal development GO:0007275 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified Bicc1 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Bicc1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Bicc1 is involved
No pathways found





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