Gene description for Rbbp7
Gene name retinoblastoma binding protein 7
Gene symbol Rbbp7
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Rbbp7
ExoCarta ExoCarta_83712
Vesiclepedia VP_83712
Entrez Gene 83712
UniProt Q71UF4  
 Rbbp7 identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
Reticulocytes 21828046    
 Gene ontology annotations for Rbbp7
Molecular Function
    RNA binding GO:0003723 ISO
    histone binding GO:0042393 IBA
    histone binding GO:0042393 ISO
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 ISO
    DNA replication GO:0006260 IEA
    chromatin remodeling GO:0006338 IBA
    chromatin remodeling GO:0006338 ISO
    regulation of DNA-templated transcription GO:0006355 IBA
    regulation of DNA-templated transcription GO:0006355 ISO
    negative regulation of cell growth GO:0030308 ISO
    negative regulation of cell growth GO:0030308 ISS
    negative regulation of DNA-templated transcription GO:0045892 ISO
    response to steroid hormone GO:0048545 IEP
    cellular heat acclimation GO:0070370 ISO
    cellular heat acclimation GO:0070370 ISS
Subcellular Localization
    histone deacetylase complex GO:0000118 ISO
    chromosome, telomeric region GO:0000781 ISO
    nucleus GO:0005634 IBA
    nucleus GO:0005634 ISO
    nucleoplasm GO:0005654 ISO
    cytosol GO:0005829 IEA
    cytosol GO:0005829 ISO
    NuRD complex GO:0016581 IBA
    NuRD complex GO:0016581 ISO
    NuRD complex GO:0016581 ISS
    NURF complex GO:0016589 ISO
    ESC/E(Z) complex GO:0035098 IBA
    ESC/E(Z) complex GO:0035098 ISO
    ESC/E(Z) complex GO:0035098 ISS
    ATPase complex GO:1904949 ISO
 Experiment description of studies that identified Rbbp7 in sEVs
1
Experiment ID 96
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
2
Experiment ID 98
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Rbbp7
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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