Gene description for Vamp8
Gene name	vesicle-associated membrane protein 8
Gene symbol	Vamp8
Other names/aliases	-
Species	Rattus norvegicus
Database cross references - Vamp8
ExoCarta	ExoCarta_83730
Vesiclepedia	VP_83730
Entrez Gene	83730
UniProt	Q9WUF4
Vamp8 identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Vamp8

Molecular Function     SNAP receptor activity GO:0005484 IBA     SNAP receptor activity GO:0005484 IDA     protein binding GO:0005515 IPI     chloride channel inhibitor activity GO:0019869 IEA     chloride channel inhibitor activity GO:0019869 ISO     syntaxin binding GO:0019905 IBA     syntaxin binding GO:0019905 IPI Biological Process     vesicle fusion GO:0006906 IBA     vesicle fusion GO:0006906 IDA     vesicle fusion GO:0006906 ISO     autophagy GO:0006914 IEA     protein transport GO:0015031 IEA     vesicle-mediated transport GO:0016192 IDA     vesicle-mediated transport GO:0016192 IEA     autophagosome membrane docking GO:0016240 IEA     autophagosome membrane docking GO:0016240 ISO     regulation of endocytosis GO:0030100 ISO     SNARE complex assembly GO:0035493 IBA     SNARE complex assembly GO:0035493 ISO     eosinophil degranulation GO:0043308 ISO     neutrophil degranulation GO:0043312 ISO     symbiont entry into host cell GO:0046718 IEA     symbiont entry into host cell GO:0046718 ISO     defense response to virus GO:0051607 IEA     establishment of localization in cell GO:0051649 ISO     membrane fusion GO:0061025 IDA     protein-containing complex assembly GO:0065003 IDA     mucus secretion GO:0070254 IBA     mucus secretion GO:0070254 IEA     mucus secretion GO:0070254 ISO     zymogen granule exocytosis GO:0070625 ISO     cellular response to type II interferon GO:0071346 ISO     autophagosome maturation GO:0097352 ISO     autophagosome maturation GO:0097352 ISS     positive regulation of pancreatic amylase secretion GO:1902278 ISO     regulation of protein localization to plasma membrane GO:1903076 IEA     regulation of protein localization to plasma membrane GO:1903076 ISO     negative regulation of secretion by cell GO:1903531 IEA     negative regulation of secretion by cell GO:1903531 ISO     positive regulation of histamine secretion by mast cell GO:1903595 IEA     positive regulation of histamine secretion by mast cell GO:1903595 ISO Subcellular Localization     cytoplasm GO:0005737 ISO     lysosome GO:0005764 ISO     lysosomal membrane GO:0005765 IDA     lysosomal membrane GO:0005765 IEA     lysosomal membrane GO:0005765 ISO     cytosol GO:0005829 IEA     cytosol GO:0005829 ISO     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IEA     plasma membrane GO:0005886 ISO     cell surface GO:0009986 ISO     membrane GO:0016020 ISO     basolateral plasma membrane GO:0016323 ISO     secretory granule GO:0030141 ISO     midbody GO:0030496 IDA     secretory granule membrane GO:0030667 ISO     SNARE complex GO:0031201 IBA     SNARE complex GO:0031201 IDA     SNARE complex GO:0031201 IEA     SNARE complex GO:0031201 ISO     early endosome membrane GO:0031901 IEA     late endosome membrane GO:0031902 IDA     late endosome membrane GO:0031902 IEA     late endosome membrane GO:0031902 ISO     vesicle GO:0031982 ISO     azurophil granule membrane GO:0035577 IEA     azurophil granule membrane GO:0035577 ISO     zymogen granule GO:0042588 ISO     zymogen granule membrane GO:0042589 IEA     basal part of cell GO:0045178 ISO     phagocytic vesicle GO:0045335 ISO     perinuclear region of cytoplasm GO:0048471 IEA     perinuclear region of cytoplasm GO:0048471 ISO     recycling endosome GO:0055037 IDA     recycling endosome GO:0055037 IEA     recycling endosome GO:0055037 ISO     mucin granule GO:0098594 IBA     mucin granule GO:0098594 IEA     mucin granule GO:0098594 ISO     basolateral part of cell GO:1990794 ISO