Gene description for Rtn4
Gene name	reticulon 4
Gene symbol	Rtn4
Other names/aliases	NI-250 Nogo Nogo-A Vp20 r rat N rat NogoA
Species	Rattus norvegicus
Database cross references - Rtn4
ExoCarta	ExoCarta_83765
Entrez Gene	83765
UniProt	Q9JK11
Rtn4 identified in exosomes derived from the following tissue/cell type
Adipocytes	25998041

Gene ontology annotations for Rtn4

Molecular Function     poly(A) RNA binding GO:0044822 ISO     protein binding GO:0005515 IPI     protein complex binding GO:0032403 IDA Biological Process     negative regulation of cell growth GO:0030308 ISO     negative regulation of axon extension GO:0030517 ISS     cerebral cortex radial glia guided migration GO:0021801 ISS     response to activity GO:0014823 IEP     positive regulation of glial cell differentiation GO:0045687 IDA     nervous system development GO:0007399 ISO     regulation of cell migration GO:0030334 ISO     axonal fasciculation GO:0007413 ISO     regulation of nervous system development GO:0051960 ISO     negative regulation of neuron projection development GO:0010977 IDA     negative regulation of neuron projection regeneration GO:0070571 IMP     cardiac epithelial to mesenchymal transition GO:0060317 ISO     negative regulation of neuron differentiation GO:0045665 IDA     positive regulation of dopamine secretion GO:0033603 IMP     regulation of sensory perception of pain GO:0051930 IDA     negative regulation of axonogenesis GO:0050771 IMP     regulation of branching morphogenesis of a nerve GO:2000172 ISO     oligodendrocyte differentiation GO:0048709 IEP     angiogenesis GO:0001525 ISO     axonogenesis GO:0007409 IBA     endoplasmic reticulum tubular network organization GO:0071786 ISO     olfactory nerve development GO:0021553 IEP     aging GO:0007568 IEP Subcellular Localization     cell projection GO:0042995 ISO     neuron projection GO:0043005 IDA     neuronal postsynaptic density GO:0097481 ISO     integral component of membrane GO:0016021 TAS     extracellular exosome GO:0070062 ISO     plasma membrane GO:0005886 IDA     integral component of endoplasmic reticulum membrane GO:0030176 ISO     cytoplasm GO:0005737 IDA     protein complex GO:0043234 IDA     neuronal cell body GO:0043025 ISO     myelin sheath GO:0043209 IDA     endoplasmic reticulum GO:0005783 ISO     endomembrane system GO:0012505 IBA     intracellular GO:0005622 ISO     nuclear envelope GO:0005635 ISS