Gene description for Lgals3
Gene name	lectin, galactoside-binding, soluble, 3
Gene symbol	Lgals3
Other names/aliases	AGE-R3 CBP30 L-34 gal-3
Species	Rattus norvegicus
Database cross references - Lgals3
ExoCarta	ExoCarta_83781
Entrez Gene	83781
UniProt	P08699
Lgals3 identified in exosomes derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Lgals3

Molecular Function     disaccharide binding GO:0048030 IDA     laminin binding GO:0043236 ISO     chemoattractant activity GO:0042056 ISO     advanced glycation end-product receptor activity GO:0050785 IDA     poly(A) RNA binding GO:0044822 ISO     IgE binding GO:0019863 ISO     Fc-gamma receptor I complex binding GO:0034988 IDA     monosaccharide binding GO:0048029 IDA Biological Process     RNA splicing GO:0008380 IEA     monocyte chemotaxis GO:0002548 ISO     mRNA processing GO:0006397 IEA     positive regulation of angiogenesis GO:0045766 IMP     negative regulation of extrinsic apoptotic signaling pathway GO:2001237 ISO     negative regulation of apoptotic process GO:0043066 IDA     positive regulation of cell proliferation GO:0008284 IMP     negative regulation of T cell receptor signaling pathway GO:0050860 ISO     positive regulation of mononuclear cell migration GO:0071677 ISO     negative regulation of cell proliferation in bone marrow GO:1903769 IDA     macrophage chemotaxis GO:0048246 ISO     regulation of T cell proliferation GO:0042129 ISO     positive regulation of serotonin secretion GO:0014064 IDA     skeletal system development GO:0001501 ISO     negative regulation of immunological synapse formation GO:2000521 ISO     positive chemotaxis GO:0050918 ISO     extracellular matrix organization GO:0030198 ISO     mononuclear cell migration GO:0071674 ISO     epithelial cell differentiation GO:0030855 ISO     signal transduction GO:0007165 IDA     regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 ISO     negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell GO:2001189 ISO     regulation of T cell apoptotic process GO:0070232 ISO     eosinophil chemotaxis GO:0048245 ISO     negative regulation of endocytosis GO:0045806 ISO     positive regulation of calcium ion import GO:0090280 ISO     innate immune response GO:0045087 IEA     neutrophil chemotaxis GO:0030593 ISO Subcellular Localization     nucleus GO:0005634 ISO     immunological synapse GO:0001772 ISO     extracellular matrix GO:0031012 ISO     plasma membrane GO:0005886 TAS     extracellular exosome GO:0070062 ISO     mitochondrial inner membrane GO:0005743 ISO     membrane GO:0016020 ISO     cytoplasm GO:0005737 ISO     extracellular space GO:0005615 ISO     external side of plasma membrane GO:0009897 ISO     proteinaceous extracellular matrix GO:0005578 ISO     spliceosomal complex GO:0005681 IEA     cell surface GO:0009986 IDA